Free Peptide Accumulation Calculator
Model how peptide concentrations build in your system over a full dosing cycle. Enter a compound's half-life, dose, and frequency to see how active levels reach steady state — plot up to five peptides simultaneously across 90 days.
Dosing tools
Peptide Accumulation Calculator
Calculate combined peptide doses with our visual guide.
Compound 1
Daily
Search and select a compound from the list.
hr
How fast concentration drops between doses. Short = quick decay, long = more buildup.
How often the dose is taken.
The dose you want to inject per administration, in mcg or mg.
1,000 mcg = 1 mg
Accumulation Results
Select at least one compound with a valid dose to generate the chart.
How peptide accumulation is calculated
Accumulation is driven by the relationship between dosing interval and half-life. When doses arrive faster than the peptide clears, concentrations build over time until a steady state is reached.
Select a peptide and confirm its half-life
Search for your peptide by name — half-life data is pre-loaded. Half-life is the time your body takes to eliminate half the active compound, and it determines how much peptide remains at the start of each subsequent dose.
Set your dosing frequency and dose size
Enter how often you dose and at what amount. When the interval between doses is shorter than the half-life, peptide concentrations build with each injection. Wider spacing lets it clear between doses and limits accumulation.
Read the steady-state chart
The calculator simulates 90 days of dosing and plots active concentration over time. Look for where the curve flattens — that's your steady state, the level reached when dose-in equals dose-out each dosing interval.
What is peptide accumulation?
Accumulation happens when a peptide's half-life is long enough that meaningful amounts remain in your system at the time of your next dose. Each injection adds to the residual concentration from the last, and over several days or weeks the active level builds until it reaches a plateau called steady state — where the amount cleared between doses equals the amount added.
Back to dosage calculatorHow half-life affects accumulation
Half-life is the single biggest factor in whether a peptide accumulates meaningfully. Understanding how it interacts with your dosing schedule tells you what to expect from the chart before you even run the calculation.
Short half-life (under 2 hours)
Peptides like BPC-157 and Ipamorelin clear quickly between doses. Daily or twice-daily dosing leads to minimal accumulation — each dose is largely eliminated before the next. Peaks are pronounced and trough levels are near zero.
Medium half-life (2–12 hours)
Many GHRP and growth hormone secretagogues fall here. With twice-daily dosing, modest accumulation occurs over the first week before reaching a stable plateau. The chart shows a gradual rise that levels off within five to ten days.
Long half-life (12–72+ hours)
Peptides such as TB-500 and CJC-1295 with DAC remain active for days. Even weekly dosing causes meaningful accumulation. Steady state may take several weeks to reach, and trough levels stay elevated between doses.
Multiple compounds
The calculator supports up to five compounds at once. Each builds its own independent accumulation curve. Overlaying them lets you see whether dosing schedules align and whether concentration peaks from different peptides coincide.
Model your cycle,before you start it.
The accumulation calculator plots 90 days of active peptide concentration based on your half-life, dose, and dosing interval. You can add up to five compounds at once to see how their curves interact — useful for spotting whether two peptides are building to similar levels or whether one is clearing well before the next dose arrives.
Try the blend calculatorPeptide accumulation calculator stats
90
day simulation
Models active peptide concentration across a full 90-day dosing cycle based on your half-life and schedule.
5
compounds at once
Stack up to five peptides simultaneously to compare accumulation curves and spot interaction patterns.
100+
peptides pre-loaded
Half-life data is pre-loaded for over 100 research peptides — select a name and the calculator fills in the rest.
More peptide calculation tools
The accumulation calculator is one of three free tools. Use the dosage calculator to get your exact syringe draw volume from a reconstituted vial, or use the blend calculator to work out ratios when two or more peptides share a single injection.
Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.