Healing
GHK-Cu
Longevity
3
Amino acids
Molecular weight
Peptide
Type
Naturally occurring copper tripeptide found in human plasma, saliva, and urine. GHK-Cu affects 31.2% of human genes and declines significantly with age—from ~200 ng/ml at age 20 to ~80 ng/ml at age 60. Known for exceptional skin regeneration, wound healing, and anti-aging properties.
Top researched benefits
Overview of GHK-Cu
Penetrates skin layers, activates fibroblasts, stimulates collagen and elastin synthesis, promotes angiogenesis, and modulates inflammatory responses. The copper ion is essential for enzyme cofactor activity in tissue repair processes.
skin regeneration
- Increases type I and III collagen production by up to 70% in human dermal fibroblasts.
- Stimulates elastin synthesis for improved skin elasticity and resilience.
- Strengthens protective barrier and improves moisture retention.
hair growth
- Promotes hair follicle enlargement and extends anagen (growth) phase.
- Improves scalp circulation and reduces inflammation.
antiinflammatory
- Regulates inflammatory cytokine production.
- Protects tissues from oxidative stress and damage.
Typical Dose
0.5-2% topical or 1-3mg injectable
Frequency
1-2x daily
Cycle Duration
8-16 weeks
Storage
Room temperature (topical) or 2-8°C (injectable)
Chemical Makeup
Key benefits
Enhanced collagen production (70% increase in type I and III)
Improved skin elasticity
Reduced fine lines and wrinkles
Accelerated wound healing
Hair growth stimulation
Antioxidant protection
Community interest
This peptide is still gaining traction in the community.
Copper Peptide | Skin Regeneration & Anti-Aging Compound
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNoGHK-Cu Molecular Information
View the scientifc details of GHK-Cu.
3
Amino Acids
GHK-Cu
Gly
Gly
Position 1
His
His
Position 2
Lys
Lys
Position 3
Molecular Weight
404.96DaChain Length
3Amino AcidsType
PeptideGHK-Cu Protocols
Most common delivery method for skin and hair applications. Available as creams, serums, and solutions.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Anti-aging skincare | 0.5 | 1 week range | Topical application |
| Hair growth stimulation | 1 | 1 week range | Scalp massage |
| Wound healing | 1 | 2 week range | Direct application |
| General skin health | 0.5 | 1 week range | Face and neck |
| Intensive repair | 2 | 1 week range | Targeted areas |
Reconstitution Instructions
Steps to reconstitute
- Cleanse skin thoroughly with gentle cleanser
- Pat skin dry and wait 5 minutes
- Apply thin, even layer to target areas
- Massage gently until fully absorbed (1-2 minutes)
- Follow with moisturizer if using serum
- Always apply sunscreen during daytime use
GHK-Cu Cycle
The GHK-Cu Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 1-2
- Improved skin texture and hydration
- Week 3-4
- Reduction in fine lines and increased skin smoothness
- Week 6-8
- Enhanced skin firmness and elasticity
- Week 8-12
- Visible improvement in skin tone and clarity
- Week 0-0
- 6-12 weeks for initial results
Dosing tools
GHK-Cu Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
mg
Enter the total amount of peptide in the vial in milligrams (as stated on the label).
The dose you want to inject per administration, in mcg or mg.
1,000 mcg = 1 mg
1 mL
2 mL
3 mL
5 mL
Custom
Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.
Injection Results
Based on your vial and dilution inputs.
GHK-Cu
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg GHK-Cu vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
1mL / 100 units
5 units
0.050 mL
Reference Guide
Dosing Cycle
- Peptide
- GHK-Cu
- Dosing
- 0.5-2% topical or 1-3mg injectable
- Dosing Frequency
- 1-2x daily
- Cycle Duration
- 8-16 weeks
- Storage
- Room temperature (topical) or 2-8°C (injectable)
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of GHK-Cu interactions with other common peptides and substances.
Healing
bpc
Longevity
BPC-157
SYNERGISTIC
Complementary tissue healing and regeneration pathways.
Healing
tb5
Longevity
TB-500
SYNERGISTIC
Enhanced wound healing and tissue repair when combined.
Side effects
Monitor: Be careful when combining GHK-Cu with Melanotan II.
Contraindications
Known copper sensitivity or Wilson's disease
Active skin infections at application site
Pregnancy or breastfeeding (injectable)
Stop signs
Severe skin irritation, burning, or persistent redness
Allergic reactions (rash, swelling, difficulty breathing)
Unusual skin discoloration or staining
Persistent metallic taste (injectable)
Worsening of skin condition after 4-6 weeks
Bad signs
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Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.
GHK-CuResearch References
GHK-Cu is a well studied compound
GHK-Cu
GHK-Cu is a well studied compound
Regenerative and Protective Actions of GHK-Cu Peptide
Demonstrates broad regenerative potential across multiple tissue types including skin, hair, and bone.
n.d.
GHK Peptide in Skin Regeneration
GHK-Cu increased elastin and collagen production in human dermal fibroblasts by up to 70%.
n.d.
GHK-Cu in Prevention of Oxidative Stress and Aging
Shows neuroprotective and antioxidant effects in aged mice at 10 mg/kg dosing.
n.d.