BPC-157

FDA APPROVAL PENDING

Extensively Studied

Healing

Longevity

BPC-157

Body Protection Compound-157 | Pentadecapeptide

Learn more

Healing

BPC-157

Longevity

Amino acid sequence

15

Amino acids

1419.5da

Molecular weight

Peptide

Type

Synthetic peptide derived from gastric juice protein, renowned for tissue repair, inflammation reduction, and GI protection capabilities. BPC-157 promotes blood vessel formation, enhances collagen synthesis, modulates growth factor expression, and protects against tissue damage through localized or systemic delivery.

Top researched benefits

Overview of BPC-157

Promotes blood vessel formation (angiogenesis), enhances collagen synthesis, modulates growth factor expression including VEGF, and protects against tissue damage through localized or systemic delivery pathways.

wound healing

  • Accelerated tendon-to-bone healing with improved biomechanical properties; most effective with localized injection.
  • Enhanced healing and reduced recovery following crush injuries and surgical procedures with direct tissue targeting.
  • Promotes blood vessel formation and improves vascularization through localized delivery.

neurological

  • Protective effects against neurotoxic agents and ischemic brain injury models.
  • Improved functional recovery and reduced tissue damage in spinal cord injury studies.
  • Enhanced peripheral nerve regeneration and functional recovery after injury.

gastrointestinal

  • Protective effects against gastric and duodenal ulcers through cytoprotective mechanisms.
  • Acceleration of intestinal healing with reduced inflammatory markers in IBD models.
  • Enhanced mucosal barrier function and accelerated epithelial regeneration.

Typical Dose

250-500mcg

Frequency

Once or twice daily

Cycle Duration

4-12 weeks depending on injury

Storage

Lyophilized: freezer long-term. Reconstituted: 2-8°C for 4-6 weeks

Chemical Makeup

Key benefits

Accelerated tendon, ligament, muscle, and bone healing

Localized tissue repair with direct targeting

Superior bioavailability

Anti-inflammatory effects

Angiogenesis promotion

Gastric and intestinal protection

Community interest

This peptide is still gaining traction in the community.

Body Protection Compound-157 | Pentadecapeptide

This overview is informational and based on aggregated descriptions from studies and user reports.

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BPC-157 Molecular Information

View the scientifc details of BPC-157.

15

Amino Acids

BPC-157

Gly

Gly

Position 1

Glu

Glu

Position 2

Pro

Pro

Position 3

Pro

Pro

Position 4

Pro

Pro

Position 5

Gly

Gly

Position 6

Lys

Lys

Position 7

Pro

Pro

Position 8

Ala

Ala

Position 9

Asp

Asp

Position 10

Asp

Asp

Position 11

Ala

Ala

Position 12

Gly

Gly

Position 13

Leu

Leu

Position 14

Val

Val

Position 15

Amino acid sequence
GlycinePosition 1
Glutamic acidPosition 2
ProlinePosition 3
ProlinePosition 4
ProlinePosition 5
GlycinePosition 6
LysinePosition 7
ProlinePosition 8
AlaninePosition 9
Aspartic acidPosition 10
Aspartic acidPosition 11
AlaninePosition 12
GlycinePosition 13
LeucinePosition 14
ValinePosition 15

Molecular Weight

1419.5Da

Chain Length

15Amino Acids

Type

Peptide

BPC-157 Protocols

Most effective for localized healing when injected near injury site. Subcutaneous injection preferred for targeted tissue repair.

GoalDosageFrequencyRoute
Tendon/Joint healing2501 week rangeSubQ near injury
Serious injury5002 week rangeSubQ near injury
General healing2501 week rangeSubQ or IM
Maintenance2501 week rangeSubQ

Reconstitution Instructions

Materials needed:

Bacteriostatic water (BAC)Insulin syringes (0.5-1 mL)Alcohol swabsPeptide vialSterile work surface

Steps to reconstitute

  1. Clean work area and hands thoroughly
  2. Calculate required BAC water volume using calculator
  3. Draw BAC water into syringe
  4. Inject slowly down vial side (not directly onto powder)
  5. Gently swirl until dissolved (never shake)
  6. Store in refrigerator, use within 28 days

BPC-157 Cycle

The BPC-157 Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.

Taking breaks between cycles may help maintain effectiveness and support better overall results.

Week 1-2
Reduced inflammation and pain at injection site
Week 2-4
Improved healing rate and tissue repair
Week 4-8
Maximum localized healing benefits

Dosing tools

BPC-157 Peptide Dosage Calculator

Calculate peptide doses with our visual syringe guide.

mg

Enter the total amount of peptide in the vial in milligrams (as stated on the label).

The dose you want to inject per administration, in mcg or mg.

1,000 mcg = 1 mg

1 mL

2 mL

3 mL

5 mL

Custom

Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.

Injection Results

Based on your vial and dilution inputs.

BPC-157

SINGLE COMPOUND

Volume per injection

0.05

mL

Concentration

10.00

mg/mL

Doses per vial

20

doses

Total injections per vial

20 injections

How it works

Based on a 10 mg BPC-157 vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.

1mL / 100 units

5 units

0.050 mL

Reference Guide

Dosing Cycle

Peptide
BPC-157
Dosing
250-500mcg
Dosing Frequency
Once or twice daily
Cycle Duration
4-12 weeks depending on injury
Storage
Lyophilized: freezer long-term. Reconstituted: 2-8°C for 4-6 weeks

Note: Triple agonist; microdose for fewer side effects

Reconstitution Tips

  • Use bacteriostatic water (BAC)contains 0.9% benzyl alcohol for preservation
  • Inject water slowlyaim down the vial wall, not directly onto powder
  • Never shakegently swirl or roll the vial until dissolved
  • Store properlyrefrigerate at 2-8°C after reconstitution
  • Use within 28 daysmost reconstituted peptides remain stable for about 4 weeks
  • Keep sterilealways clean vial tops with alcohol before drawing

Peptide Interactions

Research suggestions of BPC-157 interactions with other common peptides and substances.

Weight

aod

Metabolic

AOD-9604

COMPATIBLE

Safe combination; different pathways. Often combined in regenerative protocols.

COMPATIBLE

Weight

ghrp

Growth

GHRP-6

COMPATIBLE

No known negative interactions.

COMPATIBLE

Weight

ipa

Growth

Ipamorelin

SYNERGISTIC

BPC-157 increases GH receptor expression, amplifying growth hormone benefits.

SYNERGISTIC

Skin

mela

Sexual

Melanotan II

COMPATIBLE

No known interactions; different mechanisms and receptor targets.

COMPATIBLE

Healing

tb5

Longevity

TB-500

SYNERGISTIC

Complementary healing mechanisms; often used together in the Wolverine Stack.

SYNERGISTIC

Side effects

Contraindications

Active cancer (due to angiogenic effects)

Pregnancy or breastfeeding

Blood thinners (consult doctor due to angiogenesis)

WADA prohibited for competitive athletes

Stop signs

Persistent injection site reactions or infection signs

Unusual swelling or rash around injection area

Severe headaches or dizziness

Allergic reactions

Persistent or worsening digestive issues

Bad signs

Collapsed, melted, or powder stuck to vial sides (heat exposure)Cloudy solution, particles, or precipitates after reconstitutionDiscoloration of powder
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Frequently asked questions

What is a peptide dosage calculator?

A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.

How do I calculate peptide dosage from a vial?

To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.

How much Bacteriostatic water should I add to a peptide vial?

Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.

How are peptides different from proteins?

Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.​

BPC-157Research References

BPC-157 is an extensively studied compound

6Research references

BPC-157

BPC-157 is an extensively studied compound

Muscle Healing Research

Accelerated quadriceps healing with improved histology, reduced inflammation, and restored function in rat models.

2006

Spinal Cord Injury Recovery

Significant functional recovery, reduced tissue damage, and improved neurological outcomes in rat models.

2019

Gastric Ulcer Protection

Cytoprotective effects against gastric ulcers through multiple protective mechanisms.

2020

VEGF and Angiogenesis Study

Pro-angiogenic effects via VEGFR2 activation, explaining wound healing mechanisms.

2017

Safety Evaluation Study

No serious adverse effects at therapeutic doses up to 1000 μg/kg for 90 days; established safety profile.

2020

Achilles Tendon Healing Study

Superior tendon healing with improved biomechanical properties and enhanced tendon-to-bone integration in rat models.

2003