Cognitive
Cerebrolysin
Longevity
23
Amino acids
Molecular weight
Blend
Type
Standardized neuropeptide preparation containing bioactive peptides and amino acids exhibiting neurotrophic and neuroprotective properties for stroke recovery, traumatic brain injury, and cognitive enhancement. Used clinically in 50+ countries.
Top researched benefits
Overview of Cerebrolysin
IV/IM administration provides optimal bioavailability and brain penetration of neuropeptides and neurotrophic factors.
cognitive
- Meta-analyses show modest cognitive improvements, though clinical significance remains debated.
- Multiple RCTs demonstrate significant ADAS-cog and CIBIC+ improvements.
- Large meta-analysis shows significant NIHSS improvements; other studies found no functional benefit.
neuroprotection
- Largest meta-analysis (1,879 patients) shows NIHSS benefits; independent analysis found no mRS improvement.
- Multiple trials including CAPTAIN series confirm GCS/GOS improvements.
- Pilot trial shows promising 6-month outcomes; requires larger confirmatory studies.
recovery
- Some studies show enhanced recovery; results vary significantly between trials.
- Early administration within 72 hours shows better outcomes than delayed treatment.
Typical Dose
10-50mL depending on indication (stroke/TBI higher doses)
Frequency
Once daily for acute conditions; 5 days weekly for chronic conditions
Cycle Duration
7-30 days depending on condition (stroke/TBI 10-30 days, dementia 4 weeks)
Storage
Room temperature ≤25°C, protected from light in original carton - never freeze
Chemical Makeup
Key benefits
Direct brain delivery
Standardized dosing
Extensive clinical evidence
Ready-to-use formulation
Used clinically in 50+ countries
Community interest
This peptide is still gaining traction in the community.
Neuropeptide Preparation | Neurological Recovery
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNoCerebrolysin Molecular Information
View the scientifc details of Cerebrolysin.
23
Amino Acids
Cerebrolysin
Asx
Asx
Position 1
Ile
Ile
Position 2
Pyl
Pyl
Position 3
Ala
Ala
Position 4
Cys
Cys
Position 5
Thr
Thr
Position 6
Ile
Ile
Position 7
Val
Val
Position 8
Glu
Glu
Position 9
Pro
Pro
Position 10
Glu
Glu
Position 11
Pro
Pro
Position 12
Thr
Thr
Position 13
Ile
Ile
Position 14
Asp
Asp
Position 15
Glu
Glu
Position 16
Met
Met
Position 17
Ile
Ile
Position 18
?
?
Position 19
Thr
Thr
Position 20
Sec
Sec
Position 21
Arg
Arg
Position 22
Glu
Glu
Position 23
Molecular Weight
0DaChain Length
23Amino AcidsType
BlendCerebrolysin Protocols
Primary administration route with well-established protocols for direct brain delivery via IV/IM.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Small Volume IV | 10 | 1 week range | Undiluted IV slow push over 3 minutes |
| Intramuscular | 5 | 1 week range | Undiluted IM injection over 3 minutes |
| Acute Stroke | 20 | 10 week range | IV infusion (diluted to 100mL minimum) |
| Traumatic Brain Injury | 20 | 7 week range | IV infusion (diluted to 100mL minimum) |
| Alzheimer's Disease | 10 | 5 week range | IV injection/infusion (2-4 cycles yearly) |
| Vascular Dementia | 10 | 5 week range | IV injection/infusion (2-4 cycles yearly) |
Reconstitution Instructions
Materials needed:
Steps to reconstitute
- Break ampoule and extract Cerebrolysin immediately before use
- For direct injection: Up to 10 mL IV undiluted (slow 3 minutes) or 5 mL IM
- For infusion: Dilute 10-50 mL to minimum 100 mL with compatible solution
- Start infusion immediately after dilution—infuse within 15 minutes
- Flush IV catheter with sodium chloride before and after administration
- Use disposable one-way infusion sets; discard after use
Cerebrolysin Cycle
The Cerebrolysin Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 1-2
- Initial neuroprotective effects; possible mild side effects (dizziness, agitation)
- Week 2-4
- Neurological improvements become apparent; cognitive function may begin to improve
- Week 4-8
- Continued recovery; motor function improvements in stroke/TBI patients
- Week 8-12
- Sustained benefits; cognitive enhancement plateaus in chronic conditions
Dosing tools
CerebrolysinBlend Dosage Calculator
Calculate blended peptide doses with our visual syringe guide.
Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.
1 mL
2 mL
3 mL
5 mL
Custom
Custom Blend Compounds
Total: 0.0 mg
The dose of the anchor peptide you want per administration, in mcg or mg.
Conversion: 1,000 mcg = 1 mg
Results
Concentration
—
Doses per vial
—
Total blend to inject
—
You'll get:
1mL / 100 units
< 1 units
0.000 mL
Dosing Guidance
Recommended Schedule
Once daily for acute conditions; 5 days weekly for chronic conditions
Supply Duration
This vial provides 0 doses (0-day supply at 250 mcg daily)
Side effects
Contraindications
Epilepsy
Severe renal insufficiency
History of severe allergic reactions to porcine products
Stop signs
Severe allergic reactions (anaphylaxis, severe rash)
New onset seizure activity
Significant cardiovascular events during administration
Severe renal dysfunction or worsening kidney function
Bad signs
Comments
0.0
0 reviews
5
4
3
2
1
No comments yet
Be the first to share your experience. Your review helps others make more informed decisions.
Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.
CerebrolysinResearch References
Cerebrolysin is a well studied compound
Cerebrolysin
Cerebrolysin is a well studied compound
CAPTAIN II Trial - Traumatic Brain Injury
Randomized controlled trial demonstrating efficacy and safety in moderate-severe TBI with improved GCS and GOS scores.
2020
Nine-Trial Stroke Meta-Analysis - Positive Results
Largest positive meta-analysis showing significant neurological improvements in 1,879 stroke patients with NNT=7.7.
2017
Conflicting Stroke Meta-Analysis - Neutral Results
Independent meta-analysis of 1,779 patients found no significant benefits in functional outcomes (mRS/BI).
2017
TBI Systematic Review - Positive Outcomes
Analysis of 8,749 TBI patients across 10 studies confirms statistically significant GCS/GOS improvements.
2023