Cognitive
Selank
Longevity
7
Amino acids
Molecular weight
Peptide
Type
Selank is a synthetic heptapeptide analog of the naturally occurring immune peptide tuftsin, developed by the Russian Academy of Sciences. It provides anxiolytic effects comparable to benzodiazepines but without sedation, amnesia, tolerance, or withdrawal.
Top researched benefits
Overview of Selank
Works through allosteric modulation of GABA-A receptors, serotonin and dopamine system optimization, enkephalin degradation inhibition, IL-6 and cytokine balance regulation, and BDNF upregulation in the hippocampus.
Anxiety
- Clinical trials show significant reduction in anxiety symptoms comparable to benzodiazepines but without sedation or amnesia.
- Research indicates effectiveness in PTSD treatment.
- Reduces anticipatory anxiety and performance stress.
Cognitive
- Improves memory consolidation and learning capacity.
- Enhanced sustained attention during demanding cognitive tasks.
- BDNF upregulation supports long-term brain health.
Immune
- Balances immune system function through cytokine regulation.
- Shows activity against influenza, HSV, and cytomegalovirus.
- Modulates inflammatory gene expression.
Storage
Reconstituted: 2-8°C, use within 30 days
Frequency
1-2x daily (morning and/or evening)
Typical Dose
250-500mcg per dose
Cycle Duration
2-8 weeks on
Chemical Makeup
Key benefits
Rapid onset anxiolytic effects
Enhanced BDNF expression (30% increase)
Improved stress resilience
Cognitive enhancement
Immune modulation
No tolerance or withdrawal
Neuroprotective effects
Community interest
This peptide is still gaining traction in the community.
Anxiolytic & Nootropic Peptide | Tuftsin Analog
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesSelank Molecular Information
View the scientifc details of Selank.
7
Amino Acids
Selank
Thr
Thr
Position 1
Lys
Lys
Position 2
Pro
Pro
Position 3
Arg
Arg
Position 4
Pro
Pro
Position 5
Gly
Gly
Position 6
Pro
Pro
Position 7
Molecular Weight
751.9DaChain Length
7Amino AcidsType
PeptideSelank Protocols
Subcutaneous injection is the primary method with well-documented protocols. Provides reliable absorption and dosing.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Mild anxiety relief | 250 | 1 week range | SubQ |
| Moderate anxiety/cognitive | 250 | 2 week range | SubQ |
| Intensive anxiety support | 500 | 1 week range | SubQ |
| Cognitive enhancement | 250 | 1 week range | SubQ |
| PTSD support | 250 | 2 week range | SubQ |
| Immune support | 250 | 1 week range | SubQ |
Reconstitution Instructions
Materials needed:
Steps to reconstitute
- Remove vial from refrigeration; allow 10-15 minutes to reach room temperature
- Clean vial tops with alcohol wipes using circular motion; air dry
- Calculate reconstitution volume for desired concentration
- Draw bacteriostatic water into insulin syringe; remove air bubbles
- Insert needle at 45-degree angle against glass wall
- Slowly inject BAC water down vial side to minimize foaming
- Remove needle and gently swirl vial (never shake vigorously)
- Allow 1-2 minutes if cloudiness remains; swirl until clear
- Verify final solution is clear and colorless
- Label with reconstitution date and concentration
- Refrigerate immediately; use within 30 days
Selank Cycle
The Selank Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Mild anxiety reduction begins
- Week 0-0
- Improved mental clarity and focus
- Week 0-0
- Enhanced stress resilience and emotional stability
- Week 0-0
- Peak cognitive enhancement effects
- Week 0-0
- Sustained benefits for several days
Dosing tools
Selank Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
Selank
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Selank vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- Selank
- Dosing
- 250-500mcg per dose
- Dosing Frequency
- 1-2x daily (morning and/or evening)
- Cycle Duration
- 2-8 weeks on
- Storage
- Reconstituted: 2-8°C, use within 30 days
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Selank interactions with other common peptides and substances.
Cognitive
sema
Longevity
Semax
SYNERGISTIC
Enhanced cognitive and anxiolytic effects when combined.
Side effects
Contraindications
Known peptide allergies
Pregnancy or breastfeeding
Consult healthcare provider with multiple psychiatric medications
Stop signs
Severe allergic reactions (rash, breathing difficulty, swelling)
Persistent injection site reactions or infection signs
Unusual mood changes or increased anxiety
Severe headaches or neurological symptoms
Contaminated product signs (unusual smell, cloudiness)
Unexplained fatigue or cognitive impairment
Skin reactions or immune hypersensitivity
Bad signs
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Frequently asked questions
What benefits can peptides offer in research?
Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
What are some exciting applications of peptides in modern science?
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
How do peptides influence health and wellness?
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Where can I find the latest studies on peptide applications?
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Are there any guidelines for using peptides in research?
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
What is the difference between peptides and proteins?
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
How should peptides be stored?
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Can peptides be taken orally?
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
SelankResearch References
Selank is a well studied compound
Selank
Selank is a well studied compound
GABAergic Gene Expression Study
Rat frontal cortex study at 300mcg/kg showed modulation of 45 genes involved in neurotransmission; GABAergic mechanism confirmed.
2016
GAD Clinical Trial
Human subjects showed significant anxiolytic and mild nootropic effects lasting up to one week post-administration.
2008
BDNF Enhancement Study
Rat hippocampus study at 250-500mcg/kg showed 30% increase in hippocampal BDNF levels.
2010
Memory Consolidation Study
Significant activation of learning processes in subjects with poor initial learning.
2007