Cognitive
Oxytocin
Hormonal
9
Amino acids
Molecular weight
Peptide
Type
Nine-amino-acid peptide hormone produced in hypothalamus, released by posterior pituitary. Functions in social bonding, trust, empathy, reproduction, childbirth, lactation. FDA-approved synthetically for labor induction and postpartum hemorrhage.
Top researched benefits
Overview of Oxytocin
Binds oxytocin receptors on uterine smooth muscle, triggering calcium influx and myometrial contractions. Stimulates prostaglandin release. In CNS, modulates GABAergic, serotonergic, dopaminergic neurotransmission; reduces cortisol and HPA axis activity.
obstetric fda approved
- Initiates or augments uterine contractions when vaginal delivery medically indicated.
- Controls postpartum bleeding through uterine contraction stimulation during third stage.
- Adjunctive therapy for incomplete or inevitable abortion in second trimester.
researchemerging
- Extensive research with mixed results on social functioning; optimal dosing unclear.
- Combined with exposure therapy; shows reduced PTSD/depression symptoms.
- Decreases amygdala reactivity to social threats; normalizes brain connectivity.
- Improves libido, arousal, orgasm intensity in both sexes.
Typical Dose
Intranasal: 20-24 IU; Injectable: 10-40 IU; Sublingual: 50-100 IU
Frequency
As needed for social/sexual support, or 1-2x daily for anxiety/PTSD protocols; max 1 dose per 24hr for sexual function
Cycle Duration
As needed for research applications; 4-12 weeks for anxiety/autism protocols
Storage
Refrigerate at 2-8°C; protect from light
Chemical Makeup
Key benefits
FDA-approved for labor induction with precise dosing via IV
Immediate onset in obstetric settings
Established safety profile in clinical use
Researched for anxiety, PTSD, autism, sexual dysfunction
Community interest
This peptide is still gaining traction in the community.
Neurohypophysial Peptide | Social Bonding & Reproductive Hormone
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNoOxytocin Molecular Information
View the scientifc details of Oxytocin.
9
Amino Acids
Oxytocin
Cys
Cys
Position 1
Tyr
Tyr
Position 2
Ile
Ile
Position 3
Gln
Gln
Position 4
Asn
Asn
Position 5
Cys
Cys
Position 6
Pro
Pro
Position 7
Leu
Leu
Position 8
Gly
Gly
Position 9
Molecular Weight
1007.2DaChain Length
9Amino AcidsType
PeptideOxytocin Protocols
IV or IM administration in clinical settings. IV provides immediate onset; requires continuous infusion and monitoring for labor use.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Labor Induction | 0.5 | — | IV (diluted) |
| Postpartum Hemorrhage Prevention | 10 | — | IM or IV infusion |
Reconstitution Instructions
Materials needed:
Steps to reconstitute
- Hospital/clinical procedure—qualified healthcare professionals only
- Dilute oxytocin in compatible IV solution per facility protocol
- Typical dilution: 10 units in 1000mL = 10 mU/mL
- Use infusion pump for precise rate control
- Monitor uterine contractions and fetal heart rate continuously
Oxytocin Cycle
The Oxytocin Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- IV: 1-3 minute onset, 30-60 minute duration; IM: 3-5 minute onset
- Week 0-0
- 15-30 minute onset, peak 30-60 minutes, 2-4 hour duration
- Week 0-0
- 30-45 minute onset, peak ~60 minutes, 2-4 hour duration
Dosing tools
Oxytocin Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
mg
Enter the total amount of peptide in the vial in milligrams (as stated on the label).
The dose you want to inject per administration, in mcg or mg.
1,000 mcg = 1 mg
1 mL
2 mL
3 mL
5 mL
Custom
Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.
Injection Results
Based on your vial and dilution inputs.
Oxytocin
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Oxytocin vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
1mL / 100 units
5 units
0.050 mL
Reference Guide
Dosing Cycle
- Peptide
- Oxytocin
- Dosing
- Intranasal: 20-24 IU; Injectable: 10-40 IU; Sublingual: 50-100 IU
- Dosing Frequency
- As needed for social/sexual support, or 1-2x daily for anxiety/PTSD protocols; max 1 dose per 24hr for sexual function
- Cycle Duration
- As needed for research applications; 4-12 weeks for anxiety/autism protocols
- Storage
- Refrigerate at 2-8°C; protect from light
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Oxytocin interactions with other common peptides and substances.
Healing
bpc
Longevity
BPC-157
COMPATIBLE
No direct interactions; different mechanisms (tissue repair vs social function).
Sexual
kis
Hormonal
Kisspeptin
SYNERGISTIC
Both involved in reproduction; kisspeptin stimulates GnRH; oxytocin enhances arousal.
Cognitive
sel
Longevity
Selank
SYNERGISTIC
Complementary anxiolytic effects—Selank modulates GABA; oxytocin acts on central receptors.
Side effects
Contraindications
Certain obstetric conditions (see prescribing info)
Pregnancy (without medical supervision)
Active sinus infection (intranasal)
Severe hyponatremia
Stop signs
Uterine hyperstimulation or fetal distress (injectable)
Severe or persistent headache
Signs of water intoxication (confusion, seizures, swelling)
Severe nasal irritation or bleeding
Allergic reaction (rash, breathing difficulty)
Bad signs
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Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.
OxytocinResearch References
Oxytocin is a fda approved compound
Oxytocin
Oxytocin is a fda approved compound
Intranasal Oxytocin in Autism Spectrum Disorder
N=290 children/adolescents; 48 IU daily; 24 weeks. Did not significantly improve social functioning vs placebo; highlights need for better patient selection.
2021
Oxytocin Augmented Prolonged Exposure Therapy for PTSD
Veterans with PTSD; 40 IU intranasal combined with PE therapy. Lower PTSD and depression symptoms; higher therapeutic alliance vs placebo.
2019
Intranasal Oxytocin for Obesity
N=61 adults with obesity; 24 IU four times daily; 8 weeks. No weight loss but significant reduction in caloric intake; improved mental health-related quality of life.
2024