Longevity
Livagen
Immunity
4
Amino acids
Molecular weight
Peptide
Type
Livagen is a Khavinson bioregulator tetrapeptide (KEDA) with significant hepatoprotective and immunomodulatory properties. Structurally similar to Epitalon, it normalizes immune and antioxidant status while restoring liver function in hepatitis conditions. Livagen is best known for its ability to decondense chromatin, activating silent genes including ribosomal genes to boost protein synthesis and cellular activity. Maximum protective effects occur during aging.
Livagen works through direct effects on DNA structure and function. It decondenses chromatin (tightly packed DNA), increasing expression of certain genes and improving the 'youthful' profile of cells. The peptide activates multiple genes in lymphocytes, including previously silent ribosomal genes, boosting protein synthesis and cell activity. It exhibits hepatoprotective effects through normalizing immune and antioxidant status in liver tissue.
Oral capsules: Room temperature. Injectable reconstituted: 2-8°C refrigerated
Daily for 10-20 days per cycle
10-20 mg daily
10-20 days
Significant hepatoprotective properties
Decondenses chromatin to activate genes
Restores liver function in hepatitis
Normalizes immune status
Improves antioxidant status
Activates ribosomal gene expression
Maximum effects occur during aging
Boosts protein synthesis and cell activity
This peptide is still gaining traction in the community.
KEDA Tetrapeptide | Liver Bioregulator
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesView the scientifc details of Livagen.
4
Amino Acids
Livagen
Lys
Lys
Position 1
Glu
Glu
Position 2
Asp
Asp
Position 3
Ala
Ala
Position 4
Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles, often repeated 2-3 times per year.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Standard protocol | 10 | 10 week range | Oral capsules |
| Maintenance | 10 | 2 week range | Oral capsules |
The Livagen Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
Dosing tools
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Based on your vial and dilution inputs.
Safe concentration range
Livagen
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Livagen vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Note: Triple agonist; microdose for fewer side effects
Research suggestions of Livagen interactions with other common peptides and substances.
Longevity
epi
Immunity
SYNERGISTIC
Structurally similar; often combined in comprehensive anti-aging protocols.
Longevity
glu
Immunity
SYNERGISTIC
Both support liver function and antioxidant status.
Longevity
vil
Immunity
COMPATIBLE
Different organ targets; can be combined in bioregulator protocols.
Active liver emergencies (seek medical care)
Known hypersensitivity
Pregnancy or breastfeeding
Allergic reactions
Unusual liver symptoms
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Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
Livagen is a moderate research compound
Livagen
Livagen is a moderate research compound
Influence of KEDA Tetrapeptide on Organism Physiological Function
KEDA exhibits hepatoprotective, immunomodulatory, and geroprotective properties with maximum effects during aging.
n.d.
Effects of Livagen Peptide on Chromatin Activation in Lymphocytes from Old People
Livagen activates chromatin decondensation and multiple genes in aged lymphocytes.
n.d.
Hepatoprotective Properties of KEDA in Hepatitis Models
KEDA normalizes immune and antioxidant status and restores liver functions in hepatitis.
n.d.
Khavinson Peptide Bioregulators
Comprehensive review of bioregulator peptides and their epigenetic mechanisms.
n.d.