Longevity
Livagen
Immunity
4
Amino acids
Molecular weight
Peptide
Type
Livagen is a Khavinson bioregulator tetrapeptide (KEDA) with significant hepatoprotective and immunomodulatory properties. Structurally similar to Epitalon, it normalizes immune and antioxidant status while restoring liver function in hepatitis conditions. Livagen is best known for its ability to decondense chromatin, activating silent genes including ribosomal genes to boost protein synthesis and cellular activity. Maximum protective effects occur during aging.
Top researched benefits
Overview of Livagen
Livagen works through direct effects on DNA structure and function. It decondenses chromatin (tightly packed DNA), increasing expression of certain genes and improving the 'youthful' profile of cells. The peptide activates multiple genes in lymphocytes, including previously silent ribosomal genes, boosting protein synthesis and cell activity. It exhibits hepatoprotective effects through normalizing immune and antioxidant status in liver tissue.
liver support
- Protects liver tissue through normalizing immune and antioxidant status.
- Restores liver functions in both acute and chronic hepatitis models.
- Shows protective properties in liver fibroid induration models.
antiaging
- Decondenses chromatin to restore youthful gene expression patterns.
- Maximum hepatoprotective effects occur during aging.
- Activates silent genes including ribosomal genes for improved protein synthesis.
immune support
- Normalizes immune function alongside liver protective effects.
Typical Dose
10-20 mg daily
Frequency
Daily for 10-20 days per cycle
Cycle Duration
10-20 days
Storage
Oral capsules: Room temperature. Injectable reconstituted: 2-8°C refrigerated
Chemical Makeup
Key benefits
Significant hepatoprotective properties
Decondenses chromatin to activate genes
Restores liver function in hepatitis
Normalizes immune status
Improves antioxidant status
Activates ribosomal gene expression
Maximum effects occur during aging
Boosts protein synthesis and cell activity
Community interest
This peptide is still gaining traction in the community.
KEDA Tetrapeptide | Liver Bioregulator
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNoLivagen Molecular Information
View the scientifc details of Livagen.
4
Amino Acids
Livagen
Lys
Lys
Position 1
Glu
Glu
Position 2
Asp
Asp
Position 3
Ala
Ala
Position 4
Molecular Weight
461.5DaChain Length
4Amino AcidsType
PeptideLivagen Protocols
Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles, often repeated 2-3 times per year.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Standard protocol | 10 | 10 week range | Oral capsules |
| Maintenance | 10 | 2 week range | Oral capsules |
Livagen Cycle
The Livagen Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Chromatin remodeling and gene expression changes begin
- Week 0-0
- Effects persist due to epigenetic changes
- Week 0-0
- Liver function improvements
- Week 0-0
- Cumulative benefits with periodic cycles
Dosing tools
Livagen Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
mg
Enter the total amount of peptide in the vial in milligrams (as stated on the label).
The dose you want to inject per administration, in mcg or mg.
1,000 mcg = 1 mg
1 mL
2 mL
3 mL
5 mL
Custom
Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.
Injection Results
Based on your vial and dilution inputs.
Livagen
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Livagen vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
1mL / 100 units
5 units
0.050 mL
Reference Guide
Dosing Cycle
- Peptide
- Livagen
- Dosing
- 10-20 mg daily
- Dosing Frequency
- Daily for 10-20 days per cycle
- Cycle Duration
- 10-20 days
- Storage
- Oral capsules: Room temperature. Injectable reconstituted: 2-8°C refrigerated
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Livagen interactions with other common peptides and substances.
Longevity
epi
Immunity
Epitalon
SYNERGISTIC
Structurally similar; often combined in comprehensive anti-aging protocols.
Longevity
glu
Immunity
Glutathione
SYNERGISTIC
Both support liver function and antioxidant status.
Longevity
vil
Immunity
Vilon
COMPATIBLE
Different organ targets; can be combined in bioregulator protocols.
Side effects
Contraindications
Active liver emergencies (seek medical care)
Known hypersensitivity
Pregnancy or breastfeeding
Stop signs
Allergic reactions
Unusual liver symptoms
Bad signs
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Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.
LivagenResearch References
Livagen is a moderate research compound
Livagen
Livagen is a moderate research compound
Influence of KEDA Tetrapeptide on Organism Physiological Function
KEDA exhibits hepatoprotective, immunomodulatory, and geroprotective properties with maximum effects during aging.
n.d.
Effects of Livagen Peptide on Chromatin Activation in Lymphocytes from Old People
Livagen activates chromatin decondensation and multiple genes in aged lymphocytes.
n.d.
Hepatoprotective Properties of KEDA in Hepatitis Models
KEDA normalizes immune and antioxidant status and restores liver functions in hepatitis.
n.d.
Khavinson Peptide Bioregulators
Comprehensive review of bioregulator peptides and their epigenetic mechanisms.
n.d.