Weight
AOD-9604
Metabolic
16
Amino acids
Molecular weight
Peptide
Type
AOD-9604 is a modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis and inhibits lipogenesis without the side effects of full growth hormone. Unlike full GH, it does not increase IGF-1, affect glucose metabolism, or cause insulin resistance.
Top researched benefits
Overview of AOD-9604
Stimulates lipolysis and inhibits lipogenesis through beta-3 adrenergic receptor upregulation, without binding to the GH receptor. Does not affect glucose metabolism or increase IGF-1 levels.
Fat Loss
- Increases fat oxidation, plasma glycerol levels, and reduces body weight in obese models without affecting glucose metabolism.
- Reduces fat synthesis and storage in adipose tissue.
- Does not cause hyperglycemia, reduce insulin secretion, or increase insulin resistance.
Joint Health
- Enhanced cartilage regeneration when combined with hyaluronic acid in osteoarthritis models.
- Synergistic effects with hyaluronic acid for joint health.
Storage
Lyophilized: room temp or freezer long-term. Reconstituted: 2-8°C for 28 days
Frequency
Once daily
Typical Dose
250-500mcg
Cycle Duration
8-12 weeks
Chemical Makeup
Key benefits
Targets fat loss through selective lipolysis
Avoids growth hormone side effects
No effect on blood glucose or insulin
Does not increase IGF-1 levels
Metabolically safer than full hGH
Emerging cartilage repair potential
Community interest
This peptide is still gaining traction in the community.
Modified hGH Fragment | Fat Loss Peptide
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesAOD-9604 Molecular Information
View the scientifc details of AOD-9604.
16
Amino Acids
AOD-9604
Tyr
Tyr
Position 1
Leu
Leu
Position 2
Arg
Arg
Position 3
Ile
Ile
Position 4
Val
Val
Position 5
Gln
Gln
Position 6
Cys
Cys
Position 7
Arg
Arg
Position 8
Ser
Ser
Position 9
Val
Val
Position 10
Glu
Glu
Position 11
Gly
Gly
Position 12
Ser
Ser
Position 13
Cys
Cys
Position 14
Gly
Gly
Position 15
Phe
Phe
Position 16
Molecular Weight
1815.1DaChain Length
16Amino AcidsType
PeptideAOD-9604 Protocols
Subcutaneous injection is the standard route. Administer in the morning on an empty stomach, wait 30 minutes before eating for optimal results.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Fat loss - Standard | 250 | 1 week range | SubQ |
| Enhanced fat loss | 400 | 1 week range | SubQ |
| Joint support | 250 | 1 week range | SubQ |
| Conservative start | 200 | 1 week range | SubQ |
Reconstitution Instructions
Materials needed:
Steps to reconstitute
- Allow vial to reach room temperature (15-20 minutes)
- Calculate required bacteriostatic water volume
- Clean vial stopper with alcohol swab
- Draw BAC water into syringe
- Inject slowly down vial side (not directly onto powder)
- Gently swirl until dissolved (never shake vigorously)
- Store reconstituted solution at 2-8°C
- Use within 28 days
AOD-9604 Cycle
The AOD-9604 Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 1-2
- Minimal noticeable effects; compound accumulating
- Week 3-4
- Subtle body composition changes may begin
- Week 5-8
- More noticeable fat loss, especially with diet and exercise
- Week 8-12
- Continued fat reduction and improved body composition
Dosing tools
AOD-9604 Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
AOD-9604
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg AOD-9604 vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- AOD-9604
- Dosing
- 250-500mcg
- Dosing Frequency
- Once daily
- Cycle Duration
- 8-12 weeks
- Storage
- Lyophilized: room temp or freezer long-term. Reconstituted: 2-8°C for 28 days
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of AOD-9604 interactions with other common peptides and substances.
Healing
bpc
Longevity
BPC-157
COMPATIBLE
Different mechanisms; sometimes combined for comprehensive healing.
Weight
sem
Metabolic
Semaglutide
COMPATIBLE
Complementary weight loss mechanisms through different pathways.
Side effects
Contraindications
Pregnancy or breastfeeding
WADA prohibited - athletes subject to testing must avoid
Stop signs
Severe injection site reactions or infection signs
Unusual swelling or persistent redness
Allergic reactions (rare)
Any concerning or unexpected symptoms
Bad signs
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Frequently asked questions
What benefits can peptides offer in research?
Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
What are some exciting applications of peptides in modern science?
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
How do peptides influence health and wellness?
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Where can I find the latest studies on peptide applications?
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Are there any guidelines for using peptides in research?
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
What is the difference between peptides and proteins?
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
How should peptides be stored?
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Can peptides be taken orally?
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
AOD-9604Research References
AOD-9604 is a well studied compound
AOD-9604
AOD-9604 is a well studied compound
Fat Oxidation and Weight Loss in Obese Mice - Heffernan et al.
AOD-9604 reduced body weight without hyperglycemia through enhanced fat oxidation.
n.d.
Beta-3 Adrenergic Receptor Mechanism - Heffernan et al.
Increased beta-3 adrenergic receptor expression comparable to lean mice.
n.d.
Oral Lipid Metabolism Effects - Heffernan et al.
Significantly reduced lipogenic activity and increased lipolytic activity.
n.d.
Cartilage Regeneration with Hyaluronic Acid - Kwon & Park
Combination accelerated cartilage regeneration in osteoarthritis models.
n.d.