Community protocol

Weight Loss and Energy

Reta, TSM, and Mots-C

85 kg

171 cm

male

For research purposes only.

Peptide Mind does not endorse this protocol. This is a user-generated research reference — not for human consumption or therapeutic use.

Log your research schedule

Add this research protocol to your calendar or print a reference copy for your lab records. For research purposes only.

Peptide Protocol Schedule

A day-by-day view of this protocol. Tap any day to see which peptides are active. Circle size reflects how many peptides are scheduled; colored dots below represent individual peptides.

October 2026
Sun
Mon
Tue
Wed
Thu
Fri
Sat
27
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31

Off cycle

No peptides scheduled on this day.

Daily Dosing Breakdown

A grouped breakdown of which peptides to take throughout this protocol. Consecutive days with the same schedule are combined. Days with no doses are omitted.

Oct 6, 2026

GLP-3 (Retatrutide) — 4 mg ↑ · Morning

Oct 13, 2026

GLP-3 (Retatrutide) — 4 mg ↑ · Morning

Oct 20, 2026

GLP-3 (Retatrutide) — 4 mg ↑ · Morning

Oct 27, 2026

GLP-3 (Retatrutide) — 4 mg ↑ · Morning

Nov 2, 2026

Tesamorelin — 2 mg · Fasted

Nov 3, 2026

GLP-3 (Retatrutide) — 6 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Nov 4–6, 2026

Tesamorelin — 2 mg · Fasted

Nov 9, 2026

Tesamorelin — 2 mg · Fasted

Nov 10, 2026

GLP-3 (Retatrutide) — 6 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Nov 11–13, 2026

Tesamorelin — 2 mg · Fasted

Nov 16, 2026

Tesamorelin — 2 mg · Fasted

Nov 17, 2026

GLP-3 (Retatrutide) — 6 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Nov 18–20, 2026

Tesamorelin — 2 mg · Fasted

Nov 23, 2026

Tesamorelin — 2 mg · Fasted

Nov 24, 2026

GLP-3 (Retatrutide) — 6 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Nov 25–27, 2026

Tesamorelin — 2 mg · Fasted

Nov 30, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 1, 2026

GLP-3 (Retatrutide) — 8 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Dec 2, 2026

Tesamorelin — 2 mg · Fasted

Dec 3, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 4, 2026

Tesamorelin — 2 mg · Fasted

Dec 7, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 8, 2026

GLP-3 (Retatrutide) — 8 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Dec 9, 2026

Tesamorelin — 2 mg · Fasted

Dec 10, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 11, 2026

Tesamorelin — 2 mg · Fasted

Dec 14, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 15, 2026

GLP-3 (Retatrutide) — 8 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Dec 16, 2026

Tesamorelin — 2 mg · Fasted

Dec 17, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 18, 2026

Tesamorelin — 2 mg · Fasted

Dec 21, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 22, 2026

GLP-3 (Retatrutide) — 8 mg ↑ · Morning

Tesamorelin — 2 mg · Fasted

Dec 23, 2026

Tesamorelin — 2 mg · Fasted

Dec 24, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 25, 2026

Tesamorelin — 2 mg · Fasted

Dec 28, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Dec 29, 2026

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Dec 30, 2026

Tesamorelin — 2 mg · Fasted

Dec 31, 2026

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 1, 2027

Tesamorelin — 2 mg · Fasted

Jan 4, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 5, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Jan 6, 2027

Tesamorelin — 2 mg · Fasted

Jan 7, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 8, 2027

Tesamorelin — 2 mg · Fasted

Jan 11, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 12, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Jan 13, 2027

Tesamorelin — 2 mg · Fasted

Jan 14, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 15, 2027

Tesamorelin — 2 mg · Fasted

Jan 18, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 19, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Jan 20, 2027

Tesamorelin — 2 mg · Fasted

Jan 21, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 22, 2027

Tesamorelin — 2 mg · Fasted

Jan 25, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 26, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Jan 27, 2027

Tesamorelin — 2 mg · Fasted

Jan 28, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Jan 29, 2027

Tesamorelin — 2 mg · Fasted

Feb 1, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Feb 2, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Feb 3, 2027

Tesamorelin — 2 mg · Fasted

Feb 4, 2027

Tesamorelin — 2 mg · Fasted

MOTS-c — 3.75 mg · Morning

Feb 5, 2027

Tesamorelin — 2 mg · Fasted

Feb 8, 2027

Tesamorelin — 2 mg · Fasted

Feb 9, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Feb 10–12, 2027

Tesamorelin — 2 mg · Fasted

Feb 15, 2027

Tesamorelin — 2 mg · Fasted

Feb 16, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Feb 17–19, 2027

Tesamorelin — 2 mg · Fasted

Feb 22, 2027

Tesamorelin — 2 mg · Fasted

Feb 23, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Feb 24–26, 2027

Tesamorelin — 2 mg · Fasted

Mar 1, 2027

Tesamorelin — 2 mg · Fasted

Mar 2, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Mar 3–5, 2027

Tesamorelin — 2 mg · Fasted

Mar 8, 2027

Tesamorelin — 2 mg · Fasted

Mar 9, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Mar 10–12, 2027

Tesamorelin — 2 mg · Fasted

Mar 15, 2027

Tesamorelin — 2 mg · Fasted

Mar 16, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Mar 17–19, 2027

Tesamorelin — 2 mg · Fasted

Mar 22, 2027

Tesamorelin — 2 mg · Fasted

Mar 23, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Mar 24–26, 2027

Tesamorelin — 2 mg · Fasted

Mar 29, 2027

Tesamorelin — 2 mg · Fasted

Mar 30, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Mar 31 – Apr 2, 2027

Tesamorelin — 2 mg · Fasted

Apr 5, 2027

Tesamorelin — 2 mg · Fasted

Apr 6, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Apr 7–9, 2027

Tesamorelin — 2 mg · Fasted

Apr 12, 2027

Tesamorelin — 2 mg · Fasted

Apr 13, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Apr 14–16, 2027

Tesamorelin — 2 mg · Fasted

Apr 19, 2027

Tesamorelin — 2 mg · Fasted

Apr 20, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Apr 21–23, 2027

Tesamorelin — 2 mg · Fasted

Apr 26, 2027

Tesamorelin — 2 mg · Fasted

Apr 27, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

Apr 28–30, 2027

Tesamorelin — 2 mg · Fasted

May 3, 2027

Tesamorelin — 2 mg · Fasted

May 4, 2027

GLP-3 (Retatrutide) — 10 mg · Morning

Tesamorelin — 2 mg · Fasted

May 5–7, 2027

Tesamorelin — 2 mg · Fasted

May 10–14, 2027

Tesamorelin — 2 mg · Fasted

May 17–21, 2027

Tesamorelin — 2 mg · Fasted

Weekly Schedule

Day-of-week breakdown for each peptide in this protocol.

Mon
Tue
Wed
Thu
Fri
Sat
Sun

GLP-3

GLP-3 (Retatrutide)

morning

subcutaneous

4 mg

Starting Dose
4 mg
Step
+2 mg every 4 weeks
Max Dose
10 mg
Cycle Duration
30 weeks 6 days

Total Peptide Requirements

The total quantity of each peptide needed to complete this protocol, calculated from dosage and duration.

Weight

GLP-3

Metabolic

GLP-3 (Retatrutide)

4–10 mg · weekly · Morning

260.6

Weight

tesa

Growth

Tesamorelin

2 mg · 5× weekly · Fasted

288.6

Metabolic

mot

Metabolic

MOTS-c

3.8 mg · twice weekly · Morning

73.9

Know exactly what to draw

Enter your vial concentration and we'll calculate the precise injection volume for every peptide in this protocol.

Protocol Body Targets

The biological systems and tissue targets addressed by the 3 peptides in this protocol.

4

Body Targets

3 peptides

Metabolic

Regulates fat metabolism, insulin sensitivity, and energy use.

GLP-3 (Retatrutide), Tesamorelin, MOTS-c

Gut

Supports gut lining integrity, digestion, and the gut-brain axis.

GLP-3 (Retatrutide)

Hormones

Influences hormone signaling pathways and endocrine balance.

Tesamorelin

Muscle

Enhances muscle growth, repair, and recovery after exercise.

MOTS-c

Protocol targeted areas

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Protocol Duration & Timeline

A visual breakdown of each peptide's active window within this protocol. Use this to understand the total cycle length and how each compound's duration compares to the full protocol.

GLP-3 (Retatrutide)

4 mg once per week

Start at 4 mg · +2 mg every 4 weeks · max 10 mg

216 days

Tesamorelin

2 mg 5x per week

202 days

MOTS-c

3.75 mg twice per week

69 days

Protocol Peptides

Each peptide included in this protocol with its dosing amount, frequency, and administration details.

Weight

GLP-3

Metabolic

GLP-3 (Retatrutide)

Preclinical

WeightMetabolic

Weight

tesa

Growth

Tesamorelin

Fda Approved

WeightGrowth

Metabolic

mot

Metabolic

MOTS-c

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Frequently asked questions

What is a peptide dosage calculator?

A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringe units to draw. This calculator works for single peptide compounds and multi-peptide blends.

How do I calculate peptide dosage from a vial?

To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.

How much Bacteriostatic water should I add to a peptide vial?

Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.

How are peptides different from proteins?

Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.​