Cognitive
NA-Selank Amidate
Longevity
7
Amino acids
Molecular weight
Peptide
Type
NA-Selank Amidate is an enhanced version of Selank, the anxiolytic nootropic peptide developed at Russia's Institute of Molecular Genetics. The N-acetyl group improves blood-brain barrier penetration and creates more stable metabolites, while the C-terminal amidation further enhances metabolic stability and receptor binding. Unlike benzodiazepines, it provides anxiety relief without sedation, dependency, or cognitive impairment.
Top researched benefits
Overview of NA-Selank Amidate
NA-Selank Amidate modulates multiple neurotransmitter systems including GABA, dopamine, and serotonin, while regulating brain-derived neurotrophic factor (BDNF). It allosterically modulates GABAA receptors without causing the sedation or dependency of benzodiazepines. The peptide activates serotonin metabolism in the hypothalamus and brainstem, and increases BDNF levels to promote neuronal growth and differentiation.
Anxiety And Mood
- Standard Selank approved in Russia for GAD; NA-Selank Amidate offers enhanced delivery.
- Modulates stress response through GABA and serotonin systems without sedation.
- Improves mood through serotonin metabolism activation.
Cognitive Enhancement
- Increases memory trace stability for up to 30 days in animal studies.
- BDNF elevation supports learning and neuroplasticity.
- BDNF increase reduces effects of neurological injury.
Immune Support
- Based on tuftsin structure, retains immunomodulatory properties.
Storage
Refrigerate at 2-8°C
Frequency
1-2x daily for 14-20 days
Typical Dose
200-500mcg per administration
Cycle Duration
2-3 weeks (14-20 days)
Chemical Makeup
Key benefits
Pronounced anxiolytic effects without sedation
Enhanced blood-brain barrier penetration (vs standard Selank)
Improved metabolic stability and longer half-life
Nootropic effects with enhanced memory and learning
Increased BDNF levels for neuroplasticity
No dependency or withdrawal effects
Immune-modulating properties
Effects persist after treatment cessation
Community interest
This peptide is still gaining traction in the community.
N-Acetyl Selank Amidate | Enhanced Anxiolytic Nootropic
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNA-Selank Amidate Molecular Information
View the scientifc details of NA-Selank Amidate.
7
Amino Acids
NA-Selank Amidate
Thr
Thr
Position 1
Lys
Lys
Position 2
Pro
Pro
Position 3
Arg
Arg
Position 4
Pro
Pro
Position 5
Gly
Gly
Position 6
Pro
Pro
Position 7
Molecular Weight
864DaChain Length
7Amino AcidsType
PeptideNA-Selank Amidate Protocols
Intranasal spray is the preferred delivery method, providing direct access to the brain while bypassing first-pass metabolism. The N-acetyl and amide modifications enhance absorption and stability.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Anxiety relief | 250 | 1 week range | Intranasal |
| Cognitive enhancement | 200 | 1 week range | Intranasal |
| Standard protocol | 300 | 1 week range | Intranasal |
NA-Selank Amidate Cycle
The NA-Selank Amidate Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Anxiolytic effects begin; reduced stress response
- Day 1-3
- Nootropic effects become noticeable
- Week 1-2
- Full anxiolytic and cognitive benefits
- Week 0-0
- Benefits persist for approximately 1 week after 14-day course
Dosing tools
NA-Selank Amidate Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
NA-Selank Amidate
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg NA-Selank Amidate vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- NA-Selank Amidate
- Dosing
- 200-500mcg per administration
- Dosing Frequency
- 1-2x daily for 14-20 days
- Cycle Duration
- 2-3 weeks (14-20 days)
- Storage
- Refrigerate at 2-8°C
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of NA-Selank Amidate interactions with other common peptides and substances.
Cognitive
sema
Longevity
Semax
SYNERGISTIC
Often combined for comprehensive cognitive enhancement and mood support.
Side effects
Contraindications
Pregnancy or breastfeeding
Known hypersensitivity to Selank or tuftsin
Severe psychiatric conditions (consult professional)
Stop signs
Allergic reactions
Paradoxical anxiety increase
Unusual mood changes
Bad signs
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Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
NA-Selank AmidateResearch References
NA-Selank Amidate is a moderate research compound
NA-Selank Amidate
NA-Selank Amidate is a moderate research compound
Selank Administration Affects Expression of Genes in GABAergic Neurotransmission
Selank modulates GABAA receptor activity, contributing to anxiolytic effects without benzodiazepine-like side effects.
n.d.
Selank Clinical Trial in Anxiety Disorders
14 days of intranasal Selank produced pronounced anxiolytic and mild nootropic effects; benefits persisted 1 week post-treatment.
n.d.
Selank and Serotonin Metabolism
Single Selank injection activated serotonin metabolism and increased memory trace stability for up to 30 days.
n.d.
Selank and BDNF Expression
Selank administration increases BDNF levels, supporting neuronal growth and memory enhancement.
n.d.