Weight
5-Amino-1MQ
Longevity
0
Amino acids
Molecular weight
Peptide
Type
5-Amino-1MQ is a small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that enhances cellular NAD+ levels and mitochondrial function. Not a true peptide, but a small molecule compound used in longevity and metabolic optimization protocols.
Top researched benefits
Overview of 5-Amino-1MQ
Inhibits NNMT enzyme systemically, preventing NAD+ degradation and maintaining elevated cellular NAD+ levels to support mitochondrial function and metabolic processes.
Longevity
- Significantly increases cellular NAD+ levels by inhibiting NNMT enzyme, supporting cellular energy production and DNA repair mechanisms essential for healthy aging.
- Improves mitochondrial biogenesis and efficiency, enhancing cellular energy production and reducing oxidative stress markers associated with aging.
- Enhanced NAD+ availability supports sirtuins and other longevity pathways involved in DNA repair, cellular maintenance, and stress resistance.
Metabolism
- Improvement through enhanced mitochondrial efficiency.
- Enhancement via cellular energy optimization.
- Improved glucose/fat substrate switching.
Weight Loss
- Supports increased basal metabolic rate.
- Improvements in fat burning capacity.
Storage
Oral: room temp. Injectable: lyophilized room temp or freezer, reconstituted 2-8°C for 28 days
Frequency
Once daily, preferably morning
Typical Dose
50-100mg oral or 150-500mcg SubQ
Cycle Duration
8-12 weeks continuous
No visual available
Due to this peptide having no amino acids, there is no molecular chain to display.
Chemical Makeup
Key benefits
Enhanced NAD+ levels
Improved mitochondrial function
Better energy metabolism
Enhanced cellular repair
Improved insulin sensitivity
Longevity support
Convenient daily oral dosing
Community interest
This peptide is still gaining traction in the community.
NNMT Inhibitor | Longevity & Metabolic Enhancement
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?Yes5-Amino-1MQ Molecular Information
View the scientifc details of 5-Amino-1MQ.
Molecular Weight
0DaChain Length
0Amino AcidsType
Peptide5-Amino-1MQ Protocols
Most common delivery method. Take with food to improve absorption and reduce potential GI effects. Consistent daily timing helps maintain steady NAD+ levels. Morning or early afternoon dosing preferred.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Conservative initiation | 25 | 1 week range | Oral with food |
| Standard starting dose | 50 | 1 week range | Oral with food |
| Typical maintenance | 75 | 1 week range | Oral with food |
| Maximum dose | 100 | 1 week range | Oral with food |
| Split dosing protocol | 50 | 2 week range | Oral with meals |
5-Amino-1MQ Cycle
The 5-Amino-1MQ Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 1-2
- Gradual energy increase and mental clarity
- Week 2-4
- Enhanced exercise performance and recovery
- Week 4-8
- Improved metabolic markers and body composition
- Week 8-12
- Sustained longevity benefits and cellular health improvements
Dosing tools
5-Amino-1MQ Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
5-Amino-1MQ
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg 5-Amino-1MQ vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- 5-Amino-1MQ
- Dosing
- 50-100mg oral or 150-500mcg SubQ
- Dosing Frequency
- Once daily, preferably morning
- Cycle Duration
- 8-12 weeks continuous
- Storage
- Oral: room temp. Injectable: lyophilized room temp or freezer, reconstituted 2-8°C for 28 days
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of 5-Amino-1MQ interactions with other common peptides and substances.
Healing
bpc
Longevity
BPC-157
COMPATIBLE
No known interactions; different mechanisms with potential complementary benefits.
Side effects
Contraindications
Pregnancy or breastfeeding
Pre-existing metabolic conditions (consult healthcare provider)
Stop signs
Severe gastrointestinal upset or persistent nausea
Unusual fatigue or weakness (opposite of expected effect)
Persistent headaches or dizziness
Sleep disturbances or insomnia
Allergic reactions (rash, swelling, difficulty breathing)
Significant mood changes or anxiety
Bad signs
Comments
0.0
0 reviews
5
4
3
2
1
No comments yet
Be the first to share your experience. Your review helps others make more informed decisions.
Frequently asked questions
What benefits can peptides offer in research?
Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
What are some exciting applications of peptides in modern science?
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
How do peptides influence health and wellness?
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Where can I find the latest studies on peptide applications?
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Are there any guidelines for using peptides in research?
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
What is the difference between peptides and proteins?
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
How should peptides be stored?
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Can peptides be taken orally?
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
5-Amino-1MQResearch References
5-Amino-1MQ is a preclinical compound
5-Amino-1MQ
5-Amino-1MQ is a preclinical compound
Mouse Obesity Study - Neelakantan et al.
Diet-induced obese mice showed 5.1% weight loss, 30% adipocyte size reduction at 60mg/kg/day. Human equivalent ~5mg/kg/day using FDA allometric scaling.
2018
Rat Pharmacokinetics Study
Demonstrated 38.4% oral bioavailability, half-life 6.9hr (oral) and 3.8hr (IV). Supports oral administration viability.
2021
Muscle Function in Aged Mice
40% grip strength improvement in sedentary mice, 60% with exercise at 10mg/kg/day SubQ for 8 weeks. No adverse effects observed.
2024