Healing
Cartalax
Longevity
3
Amino acids
Molecular weight
Peptide
Type
Cartalax is a synthetic tripeptide (Ala-Glu-Asp) developed at the St. Petersburg Institute of Bioregulation and Gerontology as a cartilage-specific peptide bioregulator. It modulates gene expression in chondrocytes and fibroblasts, promoting extracellular matrix synthesis and suppressing degenerative signaling pathways. Used in longevity and joint health research, it is primarily studied in Russian preclinical models with no registered Western clinical trials.
Top researched benefits
Overview of Cartalax
Cartalax operates through epigenetic bioregulation in chondrocytes, upregulating synthesis of Type II collagen and aggrecan while downregulating matrix metalloproteinases (MMPs) responsible for cartilage degradation. It also reduces caspase-3 expression in chondrocyte cell lines and has been linked to increased SIRT6 activity, suppressing aging-associated markers p16, p21, and p53.
joint health
- Clinical efficacy shown in osteochondrosis, osteoarthritis, and osteoporosis treatment.
- Supports cartilage maintenance and joint function.
- Supports bone and connective tissue healing.
skin health
- Increased Ki-67 expression with suppressed apoptosis in young and aged cells.
- Enhances collagen synthesis in connective tissue.
- Inhibited MMP-9 synthesis; maintained extracellular matrix integrity.
Typical Dose
10mg per injection
Frequency
once daily
Cycle Duration
10 consecutive days, repeated every 3–6 months
Storage
Lyophilized: -20°C for long-term stability, protected from light and moisture. Reconstituted: 2–8°C for up to 28–30 days, avoid freeze-thaw cycles.
Chemical Makeup
Key benefits
Upregulates Type II collagen and aggrecan synthesis in chondrocytes, supporting cartilage matrix integrity and thickness
Downregulates matrix metalloproteinases (MMPs), slowing enzymatic degradation of articular cartilage
Reduces caspase-3 expression in chondrocyte cell lines, decreasing apoptosis in joint tissue
Increases SIRT6 activity and suppresses p16, p21, and p53 markers, decelerating cellular aging in cartilage
Community interest
This peptide is still gaining traction in the community.
Cartilage Bioregulator | Joint Health & Longevity
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNoCartalax Molecular Information
View the scientifc details of Cartalax.
3
Amino Acids
Cartalax
Ala
Ala
Position 1
Glu
Glu
Position 2
Asp
Asp
Position 3
Molecular Weight
333.29DaChain Length
3Amino AcidsType
PeptideCartalax Protocols
Subcutaneous injection is the exclusively documented delivery route for Cartalax, a tripeptide bioregulator (Ala-Glu-Asp) targeting cartilage and connective tissue regeneration. Injections are administered once daily for 10–20 consecutive day courses, 2–3 times per year, with the preferred site being the abdomen or near the affected joint.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Cartilage repair and early osteoarthritis | 200 | 1 day range | SubQ near affected joint |
| Cellular senescence and gene expression modulation | 50 | 1 day range | SubQ |
| Systemic anti-aging and gerontology | 100 | 1 day range | SubQ |
| Tissue-specific protein synthesis support | 100 | 1 day range | SubQ near target tissue |
| Chronic joint health maintenance (between intensive courses) | 200 | 3 week range | SubQ |
| Connective tissue and extracellular matrix homeostasis | 20 | 1 day range | SubQ |
Reconstitution Instructions
Materials needed:
Steps to reconstitute
- Allow the Cartalax lyophilized vial to reach room temperature for 10–15 minutes before reconstitution.
- Wipe the vial stopper with an alcohol prep pad and allow it to air-dry for 30 seconds.
- Draw 2.0 mL of bacteriostatic water into a syringe for a 5 mg vial, yielding a 2.5 mg/mL (2,500 mcg/mL) concentration. For a 20 mg vial, draw 3.0 mL to yield approximately 6,670 mcg/mL.
- Insert the needle through the vial stopper and inject the bacteriostatic water slowly down the inside wall of the vial — never directly onto the powder.
- Gently swirl or roll the vial between your palms until the powder is fully dissolved. Do not shake the vial.
- Store the reconstituted vial in the refrigerator at 2–8°C and use within 28 days.
- For each injection, wipe the vial stopper with a fresh alcohol prep pad, then draw the desired dose into an insulin syringe. For a 50 mcg dose from a 2.5 mg/mL solution, draw 0.02 mL (2 units on a U-100 syringe); for a 200 mcg dose, draw 0.08 mL (8 units).
- Pinch a fold of skin at the injection site (abdomen, thigh, or near the affected joint), insert the needle at a 45–90 degree angle, and inject slowly and steadily without aspirating.
- Rotate injection sites with each dose to avoid localized tissue irritation or lipohypertrophy.
Cartalax Cycle
The Cartalax Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 1-2
- Establishing baseline; minimal noticeable changes
- Week 3-4
- Gradual improvement in joint comfort
- Week 0-0
- Noticeable mobility improvements
- Week 0-0
- Maximum therapeutic effect achieved
Dosing tools
Cartalax Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
mg
Enter the total amount of peptide in the vial in milligrams (as stated on the label).
The dose you want to inject per administration, in mcg or mg.
1,000 mcg = 1 mg
1 mL
2 mL
3 mL
5 mL
Custom
Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.
Injection Results
Based on your vial and dilution inputs.
Cartalax
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Cartalax vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
1mL / 100 units
5 units
0.050 mL
Reference Guide
Dosing Cycle
- Peptide
- Cartalax
- Dosing
- 10mg per injection
- Dosing Frequency
- once daily
- Cycle Duration
- 10 consecutive days, repeated every 3–6 months
- Storage
- Lyophilized: -20°C for long-term stability, protected from light and moisture. Reconstituted: 2–8°C for up to 28–30 days, avoid freeze-thaw cycles.
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Cartalax interactions with other common peptides and substances.
Side effects
Contraindications
Pregnancy and breastfeeding
Active cancer (theoretical proliferation risk)
Stop signs
Allergic reactions
Digestive upset (rare with proper administration)
No improvement after 3 months
Unexpected symptoms
Bad signs
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Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.
CartalaxResearch References
Cartalax is a preclinical compound
Cartalax
Cartalax is a preclinical compound
Fibroblast Proliferation Study
Human skin fibroblasts; 72 hours at 20 nM. Increased Ki-67 expression with suppressed apoptosis in young and aged cells.
2019
Kidney Cell Culture Research
Renal epithelial cells; 7 days. Reduced pro-apoptotic p53 expression in aging kidney cells.
2020
Clinical Spine & Joint Study (Russia)
Human subjects; 1-3 months with 0.1mg capsules daily. Efficacy in osteochondrosis, osteoarthritis, and osteoporosis treatment.
n.d.
Matrix Metalloproteinase Research
Fibroblast cultures; 5 days at 20 nM. Inhibited MMP-9 synthesis; maintained extracellular matrix integrity.
2020
Calculate peptide dosages
Learning how to calculate a peptide dose? Use our beginner-friendly peptide dosage, blend, and accumulation calculators. Enter vial size, reconstitution volume, and target dose to get exact draw volumes instantly. No guesswork, just clear guidance that helps prevent common mistakes.
