Longevity
Crystagen
Immunity
3
Amino acids
Molecular weight
Peptide
Type
Crystagen is a Khavinson bioregulator tripeptide (EDP) identified in thymalin with selective action on thymus tissues. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology, it enhances immune function by stimulating normal lymphocyte proliferation while inhibiting tumor cell growth. Research shows effectiveness in normalizing immunity in 82% of elderly patients (vs 56% control) and reducing respiratory infections in athletes by doubling HSP gene expression.
Top researched benefits
Overview of Crystagen
Crystagen works through epigenetic regulation by influencing gene expression and protein synthesis in immune cells. It regulates the synthesis of heat-shock proteins, cytokines, and affects cell differentiation, proliferation, and apoptosis. The EDP peptide enhances spontaneous proliferative activity of normal lymphocytes while inhibiting proliferation of tumor cells (K-562 erythromyelosis). It activates B-cell immune system and thymic epithelial cells (VTEC2.H/S).
Immune Support
- Normalizes immunogram in elderly patients with impaired immunity.
- Restores immune function after infectious diseases.
- Helps normalize immunity after radiation and chemotherapy exposure.
Stress Resistance
- Increases stress resistance and reduces respiratory infections in athletes.
- Doubles expression of heat-shock protein gene HSPA1A.
Antitumor
- Inhibits proliferation of K-562 human erythromyelosis tumor cells.
Storage
Capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated
Frequency
Once daily for 10-20 consecutive days
Typical Dose
10-20 mg daily
Cycle Duration
10-20 days per cycle
Chemical Makeup
Key benefits
Normalizes immune function in 82% of patients
Stimulates normal lymphocyte proliferation
Inhibits tumor cell growth (antitumor activity)
Doubles HSP gene expression (stress resistance)
Reduces respiratory viral infections
Activates B-cell immune system
Normalizes IL-6 expression
Effective after radiation/chemotherapy
Community interest
This peptide is still gaining traction in the community.
EDP Tripeptide | Thymus Immune Bioregulator
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesCrystagen Molecular Information
View the scientifc details of Crystagen.
3
Amino Acids
Crystagen
Glu
Glu
Position 1
Asp
Asp
Position 2
Pro
Pro
Position 3
Molecular Weight
359DaChain Length
3Amino AcidsType
PeptideCrystagen Protocols
Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles, often repeated 2-3 times per year.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Standard protocol | 10 | 10 week range | Oral capsules |
| Maintenance | 10 | 2 week range | Oral capsules |
| Athletic support | 10 | 1 week range | Oral capsules |
Crystagen Cycle
The Crystagen Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Immune activation and gene expression modulation begins
- Week 0-0
- Effects persist due to epigenetic changes
- Week 0-0
- Measurable immune function improvements
- Week 0-0
- Cumulative benefits with periodic cycles
Dosing tools
Crystagen Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
Crystagen
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Crystagen vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- Crystagen
- Dosing
- 10-20 mg daily
- Dosing Frequency
- Once daily for 10-20 consecutive days
- Cycle Duration
- 10-20 days per cycle
- Storage
- Capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Crystagen interactions with other common peptides and substances.
Longevity
epi
Immunity
Epitalon
SYNERGISTIC
Often combined in comprehensive anti-aging Khavinson protocols.
Longevity
thy
Immunity
Thymalin
SYNERGISTIC
Crystagen (EDP) is derived from thymalin; complementary immune effects.
Longevity
vil
Immunity
Vilon
SYNERGISTIC
Both have immunoprotecting properties; different mechanisms complement each other.
Side effects
Contraindications
Active autoimmune flares (consult physician)
Known hypersensitivity
Pregnancy or breastfeeding
Stop signs
Allergic reactions
Unusual immune symptoms
Bad signs
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Frequently asked questions
What benefits can peptides offer in research?
Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
What are some exciting applications of peptides in modern science?
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
How do peptides influence health and wellness?
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Where can I find the latest studies on peptide applications?
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Are there any guidelines for using peptides in research?
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
What is the difference between peptides and proteins?
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
How should peptides be stored?
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Can peptides be taken orally?
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
CrystagenResearch References
Crystagen is a moderate research compound
Crystagen
Crystagen is a moderate research compound
The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity
EDP (crystagen) identified in thymalin; regulates gene expression, HSP synthesis, cytokines, and cell differentiation.
n.d.
Crystagen in Elderly Patients with Impaired Immunity
Crystagen normalized immunogram in 82% of patients vs 56% in control group.
n.d.
Peptide Bioregulators in Athletes
Crystagen doubled HSP gene expression, normalized IL-6, and reduced respiratory infections in athletes.
n.d.
EDP Peptide Effects on Lymphocyte Proliferation
EDP enhances normal lymphocyte proliferation while inhibiting K-562 tumor cell proliferation.
n.d.