Longevity
Crystagen
Immunity
3
Amino acids
Molecular weight
Peptide
Type
Crystagen is a Khavinson bioregulator tripeptide (EDP) identified in thymalin with selective action on thymus tissues. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology, it enhances immune function by stimulating normal lymphocyte proliferation while inhibiting tumor cell growth. Research shows effectiveness in normalizing immunity in 82% of elderly patients (vs 56% control) and reducing respiratory infections in athletes by doubling HSP gene expression.
Top researched benefits
Overview of Crystagen
Crystagen works through epigenetic regulation by influencing gene expression and protein synthesis in immune cells. It regulates the synthesis of heat-shock proteins, cytokines, and affects cell differentiation, proliferation, and apoptosis. The EDP peptide enhances spontaneous proliferative activity of normal lymphocytes while inhibiting proliferation of tumor cells (K-562 erythromyelosis). It activates B-cell immune system and thymic epithelial cells (VTEC2.H/S).
immune support
- Normalizes immunogram in elderly patients with impaired immunity.
- Restores immune function after infectious diseases.
- Helps normalize immunity after radiation and chemotherapy exposure.
stress resistance
- Increases stress resistance and reduces respiratory infections in athletes.
- Doubles expression of heat-shock protein gene HSPA1A.
antitumor
- Inhibits proliferation of K-562 human erythromyelosis tumor cells.
Typical Dose
10-20 mg daily
Frequency
Once daily for 10-20 consecutive days
Cycle Duration
10-20 days per cycle
Storage
Capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated
Chemical Makeup
Key benefits
Normalizes immune function in 82% of patients
Stimulates normal lymphocyte proliferation
Inhibits tumor cell growth (antitumor activity)
Doubles HSP gene expression (stress resistance)
Reduces respiratory viral infections
Activates B-cell immune system
Normalizes IL-6 expression
Effective after radiation/chemotherapy
Community interest
This peptide is still gaining traction in the community.
EDP Tripeptide | Thymus Immune Bioregulator
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesNoCrystagen Molecular Information
View the scientifc details of Crystagen.
3
Amino Acids
Crystagen
Glu
Glu
Position 1
Asp
Asp
Position 2
Pro
Pro
Position 3
Molecular Weight
359DaChain Length
3Amino AcidsType
PeptideCrystagen Protocols
Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles, often repeated 2-3 times per year.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Standard protocol | 10 | 10 week range | Oral capsules |
| Maintenance | 10 | 2 week range | Oral capsules |
| Athletic support | 10 | 1 week range | Oral capsules |
Crystagen Cycle
The Crystagen Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Immune activation and gene expression modulation begins
- Week 0-0
- Effects persist due to epigenetic changes
- Week 0-0
- Measurable immune function improvements
- Week 0-0
- Cumulative benefits with periodic cycles
Dosing tools
Crystagen Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
mg
Enter the total amount of peptide in the vial in milligrams (as stated on the label).
The dose you want to inject per administration, in mcg or mg.
1,000 mcg = 1 mg
1 mL
2 mL
3 mL
5 mL
Custom
Volume of bacteriostatic water you add to reconstitute the powder. Use BAC water for preservation.
Injection Results
Based on your vial and dilution inputs.
Crystagen
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Crystagen vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
1mL / 100 units
5 units
0.050 mL
Reference Guide
Dosing Cycle
- Peptide
- Crystagen
- Dosing
- 10-20 mg daily
- Dosing Frequency
- Once daily for 10-20 consecutive days
- Cycle Duration
- 10-20 days per cycle
- Storage
- Capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Crystagen interactions with other common peptides and substances.
Longevity
epi
Immunity
Epitalon
SYNERGISTIC
Often combined in comprehensive anti-aging Khavinson protocols.
Longevity
thy
Immunity
Thymalin
SYNERGISTIC
Crystagen (EDP) is derived from thymalin; complementary immune effects.
Longevity
vil
Immunity
Vilon
SYNERGISTIC
Both have immunoprotecting properties; different mechanisms complement each other.
Side effects
Contraindications
Pregnancy or breastfeeding
Active autoimmune flares (consult physician)
Known hypersensitivity
Stop signs
Allergic reactions
Unusual immune symptoms
Bad signs
Comments
0.0
0 reviews
5
4
3
2
1
No comments yet
Be the first to share your experience. Your review helps others make more informed decisions.
Frequently asked questions
What is a peptide dosage calculator?
A peptide dosage calculator is a free tool that converts your vial size, bacteriostatic water volume, and target dose into an exact syringe draw volume. Instead of doing the reconstitution math by hand, you enter three inputs and instantly get the concentration of your solution and how many milliliters or syringeunits to draw. This calculator works for single peptide compounds and multi-peptide blends.
How do I calculate peptide dosage from a vial?
To calculate your peptide dose, divide the total peptide content of your vial in micrograms by the volume of bacteriostatic water you added in milliliters. This gives you your solution concentration in mcg/mL. Then divide your target dose by that concentration to get your draw volume. For example, a 5mg (5,000 mcg) vial reconstituted with 2mL of BAC water gives a concentration of 2,500 mcg/mL. A 250 mcg dose would require drawing 0.1mL. This calculator automates all of those steps instantly.
How much Bacteriostatic water should I add to a peptide vial?
Most people add 2mL to 3mL of bacteriostatic water per vial, but the right amount depends on the dose you want to draw and the syringe size you are using. Adding 1mL to a 5mg vial gives you a concentration of 5,000 mcg/mL, making each dose very small in volume. Adding 2mL gives you 2,500 mcg/mL, which is easier to measure on a standard insulin syringe. A general guideline is to choose a volume that puts your typical dose somewhere between 10 and 30 units on a U-100 syringe. Use the calculator above to test different water volumes and find what works for your dose.
How are peptides different from proteins?
Both are made of amino acids, but peptides are much smaller than proteins. Because of their tiny size, peptides can act like tiny messengers in the body, sending specific signals to your cells to tell them exactly what to do.
CrystagenResearch References
Crystagen is a moderate research compound
Crystagen
Crystagen is a moderate research compound
The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity
EDP (crystagen) identified in thymalin; regulates gene expression, HSP synthesis, cytokines, and cell differentiation.
n.d.
Crystagen in Elderly Patients with Impaired Immunity
Crystagen normalized immunogram in 82% of patients vs 56% in control group.
n.d.
Peptide Bioregulators in Athletes
Crystagen doubled HSP gene expression, normalized IL-6, and reduced respiratory infections in athletes.
n.d.
EDP Peptide Effects on Lymphocyte Proliferation
EDP enhances normal lymphocyte proliferation while inhibiting K-562 tumor cell proliferation.
n.d.