Reviewed by the PeptideMind Team ยท Updated August 5, 2026
GHRP-2 Dosage Calculator, Benefits & Side Effects
GHRP-2 (Pralmorelin) dosage calculator: find how much to inject for GH release, lean mass, recovery and fat loss, plus cardioprotective research and side effects to know.
GHRP-2 Dosage Schedule
One fasted shot before bed to trigger a growth hormone release, with less appetite stimulation than similar peptides like GHRP-6.
GHRP-2 Nightly Growth Hormone Release
10 weeks, focused on growth hormone support.
Daily dosing
Taken daily at night, on an empty stomach.
100 mcg per injection
100 mcg per injection, given just under the skin in the abdomen or thigh.
GHRP-2 triggers growth hormone release and causes less hunger than a similar peptide, GHRP-6. Its short half-life means a single nightly dose is a gentler entry point before adding a second daily dose.
What is GHRP-2?
GHRP-2 is a lab-made, short peptide that strongly triggers the pituitary gland to release growth hormone. It's approved in Japan as a diagnostic tool for testing growth hormone deficiency, making it the only version of this type of peptide with any official government approval; it is not FDA-approved in the US. It's used in research and biohacking communities for body composition, recovery, and anti-aging support.
Growth
ghr
Growth
Our top-rated vendor
Our rankings are based solely on third-party lab testing rigor, COA transparency, and pricing, no paid placements, no affiliate influence. We update this list as new data comes in.
Based on current scores, this vendor ranks highest across those criteria.
What Does GHRP-2 Do?
It attaches to a receptor in the pituitary gland and hypothalamus that triggers growth hormone release, using the same internal signals as the 'hunger hormone' ghrelin. It also binds a separate cell-protection receptor that can shield tissue from stress and inflammation, independent of its growth hormone effect.
Mimics the hunger hormone
Attaches to a pituitary and hypothalamus receptor, like ghrelin does.
Triggers GH release
Sets off the internal signals that release growth hormone.
Also protects tissue
Binds a separate receptor that shields tissue from stress, independent of GH.
GHRP-2 Targeted areas
Frequently Asked Questions About GHRP-2
Straight answers on reconstitution, dosing, and safety, everything you need to research with confidence. For research reference only.
GHRP-2 Reconstitution Guide
GHRP-2 is supplied as a freeze-dried powder that must be mixed into a injectable solution before use. Available in 5mg, 10mg sizes.
5 mg lyophilized vial
GHRP-2 is supplied as a freeze-dried powder that must be mixed into a injectable solution before use. Available in 5mg, 10mg sizes.
3 mL bacteriostatic water
Adding 3 mL of bac water to a 5 mg vial gives a workable concentration for syringe dosing. More water makes microdosing easier; less concentrates each draw.
Storage after mixing
Freeze the dry powder, though it can handle room temperature for a few weeks. Once mixed with bacteriostatic water, refrigerate and use within about a month; avoid freezing and thawing it repeatedly, and split it into smaller portions if needed. After reconstitution, keep the vial refrigerated and use within 30 days.
Reconstitution steps
Remove caps & sanitize stoppers
Attach needle to syringe
Draw 3 mL bacteriostatic water
Insert needle into GHRP-2 vial
Release water gently down the side
Swirl to dissolve โ don't shake
Check for full dissolution
Refrigerate GHRP-2 โ good for 30 days
Chemical Makeup
6
Amino Acids
GHRP-2
Ala
APosition 1
?
XPosition 2
Ala
APosition 3
Trp
WPosition 4
Phe
FPosition 5
Lys
KPosition 6
What Are the Benefits of GHRP-2?
What research says it may help with, and how it works in the body.
growth hormone enhancement
Used in Japan as a diagnostic tool to test for growth hormone deficiency in clinical settings.
Triggers the body's own release of growth hormone by activating ghrelin receptors, the same receptors that respond to the hunger hormone ghrelin.
Indirectly raises IGF-1 levels, a growth-related hormone, by boosting growth hormone release.
body composition
Improves fat breakdown and body composition by increasing fat-burning through growth hormone activity.
Speeds up recovery from exercise and improves sleep quality.
Boosts muscle protein building by raising growth hormone and IGF-1 levels.
protective effects
Helps protect muscle in models of muscle wasting by stimulating the GHS-R1a receptor, the same receptor that responds to growth-hormone-releasing signals.
Shown to help protect cells from damage in research on heart tissue.
What Are the Side Effects of GHRP-2?
Who should avoid it, warning signs to watch for, and what to know before combining it with other compounds.
Who Should Avoid It
Active cancer or history of cancer
Pregnancy or breastfeeding
Pituitary disorders
Diabetic retinopathy
WADA prohibited for competitive athletes
Stop Right Away If You Notice
Severe or persistent headaches
Unusual swelling in hands or feet
Signs of carpal tunnel syndrome
Allergic reactions
Milder Signs to Watch For
Is GHRP-2 FDA approved?
GHRP-2 is not an FDA-approved drug. It is intended for research purposes only and is not approved for human consumption, diagnostic, or therapeutic use.
Research Use Only
GHRP-2 has not been evaluated by the FDA for safety or efficacy in humans.
No Clinical Oversight
Not manufactured under FDA-regulated quality or clinical standards.
Unregulated Sourcing
Purity, dosing, and sourcing are not verified through FDA testing or oversight.

GHRP-2 Cycle Length: How Long Should It Last?
This breaks down how long a typical GHRP-2 cycle runs and what research suggests happens at each stage. Research shows that staying on a peptide continuously, without a break, may make it less effective over time.
That's why most research protocols build in a break between cycles, often called a washout period, to let the body reset before starting again.
- Week 0-0
- GH spike within 15-30 minutes of injection
- Week 1-2
- Improved sleep quality and recovery
- Week 2-4
- Noticeable improvements in energy and well-being
- Week 4-8
- Visible changes in body composition and muscle fullness
- Week 8-12
- Full benefits realized with consistent use
GHRP-2 Research References
It is an approved compound
GHRP-2
GHRP-2 is an approved compound
GHRP-2 infusion increased food intake by 35.9% compared to saline, demonstrating ghrelin-like orexigenic effects.
n.d.
GHRPs including GHRP-2 demonstrated significant cytoprotective effects in cardiac and extracardiac tissues.
n.d.
Chronic GHRP-2 administration increased average daily gain by 22.35% and feed efficiency by 20.64%.
n.d.
