Longevity
Vilon
Immunity
2
Amino acids
Molecular weight
Peptide
Type
Vilon is a Khavinson bioregulator dipeptide (KE) consisting of lysine and glutamic acid, originally isolated from thymus gland extracts. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it acts as a molecular signaling compound that restores normal gene expression and protein synthesis in immune and epithelial cells. Research shows Vilon increases mean lifespan by 20-40% in animal studies and suppresses tumor development.
Top researched benefits
Overview of Vilon
Vilon works through epigenetic modulation, restoring chromatin structure and gene expression in immune cells. It stimulates thymocyte proliferation, activates T-helper cells, and increases the proliferative index in thymus tissue (from 26% to 37% in studies). The peptide modulates tyrosine phosphorylation of mitogen-activated cytoplasmic kinases and helps rejuvenate aged immune systems by restoring proper gene expression patterns.
Immune Support
- Stimulates thymocyte proliferation and enlarges thymic lobules.
- Activates T-helper cells and improves immune response.
- Restores chromatin structure and gene expression in aged lymphocytes.
Antiaging
- Long-term treatment increased mean lifespan 20-40% in rodent studies.
- Suppresses development of spontaneous and induced tumors.
- Promotes recovery in tissues exposed to radiation damage.
Gi Health
- Restores brush border membrane enzyme levels in aged animals.
- Enhances intestinal barrier function in aged rats.
Storage
Oral capsules: room temperature; Lyophilized powder/reconstituted: 2-8°C refrigerated
Frequency
Daily for 10-20 consecutive days (Khavinson bioregulator cycle)
Typical Dose
10-20 mg per day (oral capsules) or 10 mg (injectable)
Cycle Duration
10-20 day cycle (typical 10 days in research)
Chemical Makeup
Key benefits
Increases mean lifespan 20-40% in animal models
Suppresses tumor development
Stimulates thymocyte proliferation
Activates T-helper cells
Restores chromatin structure in aged lymphocytes
Enhances intestinal barrier function
Improves enzyme activity in aged tissue
Part of comprehensive longevity protocols
Community interest
This peptide is still gaining traction in the community.
KE Dipeptide | Thymus Immune Bioregulator
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesVilon Molecular Information
View the scientifc details of Vilon.
2
Amino Acids
Vilon
Lys
Lys
Position 1
Glu
Glu
Position 2
Molecular Weight
275DaChain Length
2Amino AcidsType
PeptideVilon Protocols
Available in capsule form for oral administration. As the shortest Khavinson peptide (just 2 amino acids), Vilon is easily absorbed orally. Typical protocol involves 10-20 day cycles, repeated 2-3 times per year.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Standard protocol | 10 | 10 week range | Oral capsules |
| Maintenance | 10 | 2 week range | Oral capsules |
Vilon Cycle
The Vilon Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Immune activation and gene expression modulation begins
- Week 0-0
- Effects persist due to epigenetic changes
- Week 0-0
- Immune function improvements
- Week 0-0
- Cumulative benefits; longevity effects in animal models
Dosing tools
Vilon Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
Vilon
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Vilon vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- Vilon
- Dosing
- 10-20 mg per day (oral capsules) or 10 mg (injectable)
- Dosing Frequency
- Daily for 10-20 consecutive days (Khavinson bioregulator cycle)
- Cycle Duration
- 10-20 day cycle (typical 10 days in research)
- Storage
- Oral capsules: room temperature; Lyophilized powder/reconstituted: 2-8°C refrigerated
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Vilon interactions with other common peptides and substances.
Longevity
cry
Immunity
Crystagen
SYNERGISTIC
Both have immunoprotecting properties; different mechanisms.
Longevity
epi
Immunity
Epitalon
SYNERGISTIC
Often combined in comprehensive anti-aging Khavinson protocols.
Longevity
thy
Immunity
Thymalin
SYNERGISTIC
Both target thymus/immune system; complementary mechanisms.
Longevity
thym
Immunity
Thymogen
COMPATIBLE
Related immune peptides; can be used in comprehensive protocols.
Side effects
Contraindications
Active autoimmune flares (consult physician)
Known hypersensitivity
Pregnancy or breastfeeding
Stop signs
Allergic reactions
Unusual immune symptoms
Bad signs
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Frequently asked questions
What benefits can peptides offer in research?
Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
What are some exciting applications of peptides in modern science?
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
How do peptides influence health and wellness?
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Where can I find the latest studies on peptide applications?
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Are there any guidelines for using peptides in research?
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
What is the difference between peptides and proteins?
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
How should peptides be stored?
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Can peptides be taken orally?
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
VilonResearch References
Vilon is a moderate research compound
Vilon
Vilon is a moderate research compound
Peptide Bioregulators Increase Lifespan
Long-term treatment with peptide preparations including Vilon increased mean lifespan 20-40% and suppressed tumorigenesis.
n.d.
Vilon Effects on Aged Lymphocytes
Vilon improved lymphocytes from old people by restoring chromatin structure and gene expression.
n.d.
Peptides Regulating Proliferative Activity in THP-1 Cells
Vilon and other Khavinson peptides modulate key proliferative patterns and tyrosine phosphorylation of kinases.
n.d.
Short Peptide Immunoprotecting Properties
Vilon and related peptides possess age-associated immunoprotecting properties in the spleen.
n.d.