Ovagen
FDA APPROVAL PENDING
Moderate Research
Longevity
Ovagen
3
Amino acids
Molecular weight
Peptide
Type
Ovagen is a Khavinson bioregulator tripeptide (EDL) with primary effects on the liver and gastrointestinal tract. Developed by Dr. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it reduces long-term liver fibrosis and protects the GI mucosal layer from antibiotics, environmental toxins, and chemotherapy. Like other bioregulators, Ovagen crosses cell and nuclear membranes to directly regulate DNA transcription patterns with tissue-specific effects.
Top researched benefits
Overview of Ovagen
Ovagen works through epigenetic regulation by crossing cell and nuclear membranes to directly regulate DNA structure and transcription patterns. It is transported into cells via POT family transporters (PEPT1, PEPT2) that specifically handle di- and tripeptides, explaining its precise tissue targeting. The peptide has tissue-specific effects on liver and GI tract, reducing fibrosis and protecting mucosal integrity.
Liver Support
- Reduces long-term fibrosis development in liver tissue.
- Protects liver through gene expression regulation.
Gi Protection
- Helps protect GI mucosal layer from various insults.
- May protect GI tract from antibiotic-induced damage.
- Protects against environmental toxin effects on GI tract.
Antiaging
- Addresses age-related liver changes through bioregulation.
- Supports GI tract function during aging.
Storage
Capsules at room temperature; reconstituted injectable at 2-8°C refrigerated
Frequency
Daily for 10-20 days per cycle
Typical Dose
10-20mg daily
Cycle Duration
10-20 days
Chemical Makeup
Key benefits
Reduces long-term liver fibrosis
Protects GI mucosal layer
Defense against antibiotic damage
Protection from environmental toxins
May protect against chemotherapy GI effects
Tissue-specific targeting via PEPT transporters
Direct DNA regulation
Part of comprehensive anti-aging protocols
Community interest
This peptide is still gaining traction in the community.
EDL Tripeptide | Liver & GI Bioregulator
This overview is informational and based on aggregated descriptions from studies and user reports.
Was it helpful?YesOvagen Molecular Information
View the scientifc details of Ovagen.
3
Amino Acids
Ovagen
Glu
Glu
Position 1
Asp
Asp
Position 2
Leu
Leu
Position 3
Molecular Weight
375DaChain Length
3Amino AcidsType
PeptideOvagen Protocols
Available in capsule form for oral administration. As a tripeptide, Ovagen is transported via PEPT1/PEPT2 transporters for targeted delivery to liver and GI tissue. Typical protocol involves 10-20 day cycles.
| Goal | Dosage | Frequency | Route |
|---|---|---|---|
| Standard protocol | 10 | 10 week range | Oral capsules |
| Maintenance | 10 | 2 week range | Oral capsules |
Ovagen Cycle
The Ovagen Cycle section explains how long a typical cycle lasts and what to expect during each phase. Over time, your body can become less responsive with continuous use.
Taking breaks between cycles may help maintain effectiveness and support better overall results.
- Week 0-0
- Gene expression modulation begins
- Week 0-0
- Effects persist due to epigenetic changes
- Week 0-0
- Liver and GI function improvements
- Week 0-0
- Cumulative benefits with periodic cycles
Dosing tools
Ovagen Peptide Dosage Calculator
Calculate peptide doses with our visual syringe guide.
0.3mL / 30 units
5 units
0.050 mL
1 mL
2 mL
3 mL
5 mL
Custom
Conversion: 1,000 mcg = 1 mg
Injection Results
Based on your vial and dilution inputs.
Safe concentration range
Ovagen
SINGLE COMPOUNDVolume per injection
0.05
mL
Concentration
10.00
mg/mL
Doses per vial
20
doses
Total injections per vial
20 injections
How it works
Based on a 10 mg Ovagen vial diluted with 1 mL of bacteriostatic water, each 500 mcg injection equals 0.05 mL.
Research Purposes Only
These calculators are provided for educational and research purposes only. Always verify calculations and consult with qualified professionals. The information provided is not medical advice. Peptides should only be used in accordance with applicable laws and regulations.
Reference Guide
Dosing Cycle
- Peptide
- Ovagen
- Dosing
- 10-20mg daily
- Dosing Frequency
- Daily for 10-20 days per cycle
- Cycle Duration
- 10-20 days
- Storage
- Capsules at room temperature; reconstituted injectable at 2-8°C refrigerated
Note: Triple agonist; microdose for fewer side effects
Reconstitution Tips
- Use bacteriostatic water (BAC) — contains 0.9% benzyl alcohol for preservation
- Inject water slowly — aim down the vial wall, not directly onto powder
- Never shake — gently swirl or roll the vial until dissolved
- Store properly — refrigerate at 2-8°C after reconstitution
- Use within 28 days — most reconstituted peptides remain stable for about 4 weeks
- Keep sterile — always clean vial tops with alcohol before drawing
Peptide Interactions
Research suggestions of Ovagen interactions with other common peptides and substances.
Longevity
epi
Immunity
Epitalon
SYNERGISTIC
Often combined in comprehensive anti-aging Khavinson protocols.
Longevity
glu
Immunity
Glutathione
SYNERGISTIC
Both support liver health through different pathways.
Longevity
liv
Immunity
Livagen
SYNERGISTIC
Complementary liver bioregulators with different sequences and mechanisms.
Side effects
Contraindications
Active liver emergencies (seek medical care)
Known hypersensitivity
Pregnancy or breastfeeding
Stop signs
Allergic reactions
Unusual GI or liver symptoms
Bad signs
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Frequently asked questions
What benefits can peptides offer in research?
Peptides can support cellular repair, immune function, metabolic health, and tissue regeneration. Research suggests they may help with recovery, sleep quality, skin health, and cognitive function, depending on the specific peptide and its mechanism of action.
What are some exciting applications of peptides in modern science?
Current research explores peptides for longevity, muscle recovery, wound healing, metabolic disorders, and neuroprotection. Scientists are also investigating peptide-based drug delivery and targeted therapies that could offer more precise treatment options.
How do peptides influence health and wellness?
Peptides work by binding to receptors on cells and triggering specific biological responses. Depending on the peptide, they may promote growth hormone release, support collagen production, modulate inflammation, or influence neurotransmitter activity—each with different implications for health and wellness.
Where can I find the latest studies on peptide applications?
Peer-reviewed journals such as Nature, Science, and specialized publications like Peptides and the Journal of Peptide Science publish ongoing research. PubMed and Google Scholar are useful for searching studies by peptide name or condition.
Are there any guidelines for using peptides in research?
Research use of peptides typically follows institutional review board (IRB) protocols and regulatory guidelines. Dosage, administration route, and safety monitoring should align with published literature and applicable regulations in your jurisdiction.
What is the difference between peptides and proteins?
Peptides are short chains of amino acids (typically under 50), while proteins are longer chains that fold into complex structures. Peptides are often more stable, easier to synthesize, and can cross cell membranes more readily, making them attractive for therapeutic applications.
How should peptides be stored?
Most peptides require refrigeration (2–8°C) and protection from light. Reconstituted peptides often have shorter stability and may need to be used within days or weeks. Always follow the manufacturer's or research protocol's storage instructions.
Can peptides be taken orally?
Some peptides are bioavailable orally, but many are broken down by digestive enzymes before reaching the bloodstream. Subcutaneous injection, nasal administration, or other routes are often used in research to improve bioavailability. The optimal route depends on the specific peptide.
OvagenResearch References
Ovagen is a moderate research compound
Ovagen
Ovagen is a moderate research compound
Khavinson Peptide Bioregulators Overview
Ovagen (EDL) is a tripeptide bioregulator with effects on liver and GI tract.
n.d.
POT Family Transporters and Peptide Bioregulators
Di- and tripeptides are transported via PEPT1/PEPT2, explaining tissue-specific targeting.
n.d.
Peptide Bioregulators and Liver Fibrosis
Short peptides reduce long-term fibrosis in liver tissue through gene expression regulation.
n.d.